Background Current diagnostic tools for prostate cancer lack specificity and sensitivity for
detecting very early lesions. DNA methylation is a stable genomic modification that is …

Despite advances in cancer diagnosis and treatment strategies, robust prognostic
signatures remain elusive in most cancers. Cell proliferation has long been recognized as a …

A resting mean pulmonary artery pressure (mPAP) of 21–24 mmHg is above the upper limit
of normal but does not reach criteria for the diagnosis of pulmonary hypertension (PH). We …

Heat-shock protein 70 (Hsp70) is frequently found on the plasma membrane of a large number
of malignant tumors including non-small cell lung cancer (NSCLC) and gets released into …

Hypoxia mediates resistance to radio(chemo)therapy (RT) by stimulating the synthesis of
hypoxia-related genes, such as osteopontin (OPN) and stress proteins, including the major …

Haswell, Intel's fourth-generation core processor architecture, delivers a range of client parts,
a converged core for the client and server, and technologies used across many products. It …

… thanks to Rick Siggins for the enthusiasm he has brought over the years to hashing out the
book’s ideas; to my sister, Laura Gunther, for designing a cover by which I would feel proud to …

Background Ewing Sarcoma (ES) patients with disseminated disease into lung and bone
have an approximate long-term survival rate of 10–30%, compelling the search for new …

Embedding sensors into objects allow them to recognize various interactions. However,
sensing usually requires active electronics that are often costly, need time to be assembled, and …

Thermal feedback has been studied for navigation purposes with directional cues and a
variety of other use cases. Yet, to date, systems providing thermal feedback were primarily …