Although thalidomide (Thal) was initially used to treat multiple myeloma (MM) because of its
known antiangiogenic effects, the mechanism of its anti-MM activity is unclear. These …

Minocycline has been demonstrated to be neuroprotective after spinal cord injury (SCI).
However, the cellular consequences of minocycline treatment on the secondary injury response …

Several studies have shown that minocycline, a semisynthetic, second-generation tetracycline
derivative, is neuroprotective in animal models of central nervous system trauma and …

Background Imaging data contains a substantial amount of information which can be difficult
to evaluate by eye. With the expansion of high throughput microscopy methodologies …

The platinum-based anticancer drugs cisplatin, carboplatin, and oxaliplatin are an important
component of chemotherapy but are limited by severe dose-limiting side effects and the …

The antiangiogenic activity of thalidomide (Thal), coupled with an increase in bone marrow
angiogenesis in multiple myeloma (MM), provided the rationale for the use of Thal in MM. …

TNF-α mediates both protective and detrimental manifestations of the host immune response.
Our previous work has shown thalidomide to be a relatively selective inhibitor of TNF-α …

1. Methane mono-oxygenase of Methylococcus capsulatus (Bath) catalyses the oxidation of
various substituted methane derivatives including methanol. 2. It is a very non-specific …

The development of the polymerase chain reaction (PCR) has often been likened to the
development of the Internet, and although this does risk overstating the impact of PCR outside …

This book gives a rigorous and practical treatment of integral equations. These are significant
because they occur in many problems in mathematics, physics and engineering and they …