User profiles for David Torrents
 | David TorrentsICREA Research Professor at the Barcelona Supercomputing Centre Verified email at bsc.es Cited by 46529 |
Enterotypes of the human gut microbiome
…, J Qin, T Sicheritz-Ponten, S Tims, D Torrents… - nature, 2011 - nature.com
Our knowledge of species and functional composition of the human gut microbiome is rapidly
increasing, but it is still based on very few cohorts and little is known about variation across …
increasing, but it is still based on very few cohorts and little is known about variation across …
[HTML][HTML] Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
Chronic lymphocytic leukaemia (CLL), the most frequent leukaemia in adults in Western
countries, is a heterogeneous disease with variable clinical presentation and evolution 1 , 2 . …
countries, is a heterogeneous disease with variable clinical presentation and evolution 1 , 2 . …
PAL2NAL: robust conversion of protein sequence alignments into the corresponding codon alignments
M Suyama, D Torrents, P Bork - Nucleic acids research, 2006 - academic.oup.com
PAL2NAL is a web server that constructs a multiple codon alignment from the corresponding
aligned protein sequences. Such codon alignments can be used to evaluate the type and …
aligned protein sequences. Such codon alignments can be used to evaluate the type and …
Non-coding recurrent mutations in chronic lymphocytic leukaemia
Chronic lymphocytic leukaemia (CLL) is a frequent disease in which the genetic alterations
determining the clinicobiological behaviour are not fully understood. Here we describe a …
determining the clinicobiological behaviour are not fully understood. Here we describe a …
Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug
Metformin is widely used in the treatment of type 2 diabetes (T2D), but its mechanism of
action is poorly defined. Recent evidence implicates the gut microbiota as a site of metformin …
action is poorly defined. Recent evidence implicates the gut microbiota as a site of metformin …
A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations
Asthma exacerbations are among the most frequent causes of hospitalization during
childhood, but the underlying mechanisms are poorly understood. We performed a genome-wide …
childhood, but the underlying mechanisms are poorly understood. We performed a genome-wide …
Genome-wide associations for birth weight and correlations with adult disease
Birth weight (BW) has been shown to be influenced by both fetal and maternal factors and in
observational studies is reproducibly associated with future risk of adult metabolic diseases …
observational studies is reproducibly associated with future risk of adult metabolic diseases …
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors,
and has been reproducibly associated with future cardio-metabolic health outcomes. In …
and has been reproducibly associated with future cardio-metabolic health outcomes. In …
Comparative Genome and Proteome Analysis of Anopheles gambiae and Drosophila melanogaster
Comparison of the genomes and proteomes of the two dipteraAnopheles gambiae and
Drosophila melanogaster, which diverged about 250 million years ago, reveals considerable …
Drosophila melanogaster, which diverged about 250 million years ago, reveals considerable …
BLUEPRINT to decode the epigenetic signature written in blood
…, HG Stunnenberg, A Tanay, D Torrents… - Nature …, 2012 - nature.com
Last October, scientists gathered in Amsterdam to celebrate the start of BLUEPRINT (http://www.
blueprint-epigenome. eu/), an EU-funded consortium that will generate epigenomic …
blueprint-epigenome. eu/), an EU-funded consortium that will generate epigenomic …