The BCL-2 family of proteins controls cell death primarily by direct binding interactions that
regulate mitochondrial outer membrane permeabilization (MOMP) leading to the irreversible …

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical, …

The conversations of 186 adolescent boys (13 to 14 years old) and their friends were
videotaped and analyzed to understand the processes of influence associated with antisocial …

Permeabilization of the outer mitochondrial membrane is the point of no return in most
programmed cell deaths. This critical step is mainly regulated by the various protein-protein and …

Glioblastoma (GBM) is the most aggressive nervous system cancer. Understanding its
molecular pathogenesis is crucial to improving diagnosis and treatment. Integrated analysis of …

We describe the landscape of somatic genomic alterations based on multidimensional and
comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify …

Background Brain metastases occur in up to 40% of all patients with systemic cancer. We
aimed to assess whether stereotactic radiosurgery provided any therapeutic benefit in a …

This study examines the close friendships of early adolescent boys in relation to antisocial
behavior. 186 13–14‐year‐old boys and their close friends were interviewed, assessed at …

The study tested alternative intervention strategies to reduce escalation in problem behaviors
among high-risk young adolescents (11 to 14 years old). A total of 158 families with young …

Cell death is essential for a plethora of physiological processes, and its deregulation
characterizes numerous human diseases. Thus, the in-depth investigation of cell death and its …