Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization
DW Roberts, G Patlewicz, PS Kern… - Chemical Research …, 2007 - ACS Publications
The goal of eliminating animal testing in the predictive identification of chemicals with the
intrinsic ability to cause skin sensitization is an important target, the attainment of which has …
intrinsic ability to cause skin sensitization is an important target, the attainment of which has …
A frameless stereotaxic integration of computerized tomographic imaging and the operating microscope
DW Roberts, JW Strohbehn, JF Hatch, W Murray… - Journal of …, 1986 - thejns.org
✓ A computer-based system has been developed for the integration and display of computerized
tomography (CT) image data in the operating microscope in the correct perspective …
tomography (CT) image data in the operating microscope in the correct perspective …
Current status of methods for defining the applicability domain of (quantitative) structure-activity relationships: The report and recommendations of ecvam workshop 52
This is the 52nd report of a series of workshops organised by the European Centre for the
Validation of Alternative Methods (ECVAM). The main objective of ECVAM, as defined in 1993 …
Validation of Alternative Methods (ECVAM). The main objective of ECVAM, as defined in 1993 …
Intraoperative brain shift and deformation: a quantitative analysis of cortical displacement in 28 cases
DW Roberts, A Hartov, FE Kennedy, MI Miga… - …, 1998 - journals.lww.com
OBJECTIVE: A quantitative analysis of intraoperative cortical shift and deformation was
performed to gain a better understanding of the nature and extent of this problem and the …
performed to gain a better understanding of the nature and extent of this problem and the …
Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy
…, MA Agostini, AV Alexopoulos, BC Jobst, DW Roberts… - Neurology, 2020 - AAN Enterprises
Objective To prospectively evaluate safety and efficacy of brain-responsive neurostimulation
in adults with medically intractable focal onset seizures (FOS) over 9 years. Methods Adults …
in adults with medically intractable focal onset seizures (FOS) over 9 years. Methods Adults …
Ordination on the basis of fuzzy set theory
DW Roberts - Vegetatio, 1986 - Springer
Fuzzy set theory is an extension of classical set theory where elements of a set have grades
of membership ranging from zero for non-membership to one for full membership. Exactly as …
of membership ranging from zero for non-membership to one for full membership. Exactly as …
Extension of the Dermal Sensitisation Threshold (DST) approach to incorporate chemicals classified as reactive
RJ Safford, AM Api, DW Roberts, JF Lalko - Regulatory Toxicology and …, 2015 - Elsevier
The evaluation of chemicals for their skin sensitising potential is an essential step in ensuring
the safety of ingredients in consumer products. Similar to the Threshold of Toxicological …
the safety of ingredients in consumer products. Similar to the Threshold of Toxicological …
Quantitative fluorescence in intracranial tumor: implications for ALA-induced PpIX as an intraoperative biomarker
…, NE Simmons, KD Paulsen, DW Roberts - Journal of …, 2011 - thejns.org
Object Accurate discrimination between tumor and normal tissue is crucial for optimal tumor
resection. Qualitative fluorescence of protoporphyrin IX (PpIX), synthesized endogenously …
resection. Qualitative fluorescence of protoporphyrin IX (PpIX), synthesized endogenously …
Coregistered fluorescence-enhanced tumor resection of malignant glioma: relationships between δ-aminolevulinic acid–induced protoporphyrin IX fluorescence …
Object The aim of this study was to investigate the relationships between intraoperative
fluorescence, features on MR imaging, and neuropathological parameters in 11 cases of newly …
fluorescence, features on MR imaging, and neuropathological parameters in 11 cases of newly …
Principles for identification of High Potency Category Chemicals for which the Dermal Sensitisation Threshold (DST) approach should not be applied
DW Roberts, AM Api, RJ Safford, JF Lalko - Regulatory Toxicology and …, 2015 - Elsevier
An essential step in ensuring the toxicological safety of chemicals used in consumer products
is the evaluation of their skin sensitising potential. The sensitising potency, coupled with …
is the evaluation of their skin sensitising potential. The sensitising potency, coupled with …