User profiles for Davide Gaudesi
 | Davide GaudesiUniversità degli studi di Milano Bicocca Verified email at unimib.it Cited by 487 |
[HTML][HTML] Helmet CPAP to treat hypoxic pneumonia outside the ICU: an observational study during the COVID-19 outbreak
Background Respiratory failure due to COVID-19 pneumonia is associated with high mortality
and may overwhelm health care systems, due to the surge of patients requiring advanced …
and may overwhelm health care systems, due to the surge of patients requiring advanced …
An unusual antithrombin-binding heparin octasaccharide with an additional 3-O-sulfated glucosamine in the active pentasaccharide sequence
The 3-O-sulfation of N-sulfated glucosamine is the last event in the biosynthesis of heparin/heparan
sulfate, giving rise to the antithrombin-binding pentasaccharide sequence AGA*IA, …
sulfate, giving rise to the antithrombin-binding pentasaccharide sequence AGA*IA, …
Effects on molecular conformation and anticoagulant activities of 1, 6-anhydrosugars at the reducing terminal of antithrombin-binding octasaccharides isolated from …
Terminal 1,6-anhydro-aminosugars (1,6-anAS) are typical structural moieties of enoxaparin,
a low-molecular-weight heparin (LMWH) widely used for prevention and treatment of …
a low-molecular-weight heparin (LMWH) widely used for prevention and treatment of …
Zfp423/ZNF423 regulates cell cycle progression, the mode of cell division and the DNA-damage response in Purkinje neuron progenitors
…, R D'Ambrosio, A Badaloni, D Gaudesi… - …, 2017 - journals.biologists.com
The Zfp423/ZNF423 gene encodes a 30-zinc-finger transcription factor involved in key
developmental pathways. Although null Zfp423 mutants develop cerebellar malformations, the …
developmental pathways. Although null Zfp423 mutants develop cerebellar malformations, the …
[HTML][HTML] Heparin dodecasaccharide containing two antithrombin-binding pentasaccharides: structural features and biological properties
The antithrombin (AT) binding properties of heparin and low molecular weight heparins are
strongly associated to the presence of the pentasaccharide sequence AGA*IA (A NAc,6S -…
strongly associated to the presence of the pentasaccharide sequence AGA*IA (A NAc,6S -…
[HTML][HTML] Benchmarking postoperative outcomes after open liver surgery for cirrhotic patients with hepatocellular carcinoma in a national cohort
…, A Libia, F Notte, DP Bernasconi, S Mori, D Gaudesi - HPB, 2022 - Elsevier
Background Benchmark analysis for open liver surgery for cirrhotic patients with hepatocellular
carcinoma (HCC) is still undefined. Methods Patients were identified from the Italian …
carcinoma (HCC) is still undefined. Methods Patients were identified from the Italian …
Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity …
…, SE Guimond, MA Skidmore, D Gaudesi… - Organic & …, 2010 - pubs.rsc.org
The activities of heparan sulfate (HS) and heparin do not correlate simply with sulfation
levels or sequence. The alternative hypothesis, that appropriate charge and conformational …
levels or sequence. The alternative hypothesis, that appropriate charge and conformational …
Flexible vs Rigid Epitope Conformations for Diagnostic- and Vaccine-Oriented Applications: Novel Insights from the Burkholderia pseudomallei BPSL2765 Pal3 …
Peptides seldom retain stable conformations if separated from their native protein structure.
In an immunological context, this potentially affects the development of selective peptide-…
In an immunological context, this potentially affects the development of selective peptide-…
Unravelling structural information from complex mixtures utilizing correlation spectroscopy applied to HSQC spectra
…, E Macchi, L Muzi, M Ferro, D Gaudesi… - Analytical …, 2013 - ACS Publications
The first use of statistical correlation spectroscopy to extract chemical information from 2D-HSQC
spectra, termed HSQC correlation spectroscopy (HSQCcos), is reported. HSQCcos is …
spectra, termed HSQC correlation spectroscopy (HSQCcos), is reported. HSQCcos is …
Construction and use of a library of bona fide heparins employing 1H NMR and multivariate analysis
In contrast to most pharmaceutical agents, the major anticoagulant agent, heparin, lacks a
uniquely defined chemical structure. It is an inherently structurally varying, poly-disperse …
uniquely defined chemical structure. It is an inherently structurally varying, poly-disperse …