The evolution of novel cell types led to the emergence of new tissues and organs during the
diversification of animals 1 . The origin of the chondrocyte, the cell type that synthesizes …

10.7554/eLife.43828.001 Cephalopod mollusks evolved numerous anatomical novelties,
including arms and tentacles, but little is known about the developmental mechanisms …

The segmental architecture of the arthropod head is one of the most controversial topics in
the evolutionary developmental biology of arthropods. The deutocerebral (second) segment …

Evolutionary developmental biology focuses on understanding the origin and evolution of
extant biological variation, and the genetic basis for this variation. The genetic toolkit appears …

In this paper, we examine prospects for the manufacture of patient-specific biomedical
implants replacing hard tissues (bone), particularly knee and hip stems and large bone (femoral) …

Cannabis is the third most used psychoactive substance worldwide. The legal status of
cannabis is changing in many Western countries, while we have very limited knowledge of the …

In Drosophila, two interacting adhesion protein families, Dprs and DIPs, coordinate the
assembly of neural networks. While intercellular DIP/Dpr interactions have been well …

BACKGROUND.: No consensus exists which patients with surgical stage 1 epithelial ovarian
should receive postoperative chemotherapy. The purpose of this study was to evaluate the …

To accelerate materials discovery, computational methods such as inverse materials design
have been proposed to predict the properties of target compounds of interest for specific …

The cohesin complex plays essential roles in chromosome segregation, 3D genome
organisation, and DNA damage repair through its ability to modify DNA topology. In higher …