Atrial fibrillation (AF) affects more than 33 million individuals worldwide 1 and has a complex
heritability 2 . We conducted the largest meta-analysis of genome-wide association studies (…

The Trans-Omics for Precision Medicine (TOPMed) programme seeks to elucidate the genetic
architecture and biology of heart, lung, blood and sleep disorders, with the ultimate goal of …

Atrial fibrillation (AF) is the most common sustained arrhythmia. Previous studies have
identified several genetic loci associated with typical AF. We sought to identify common genetic …

Background— Genetic studies have identified ion channel gene variants in families segregating
atrial fibrillation (AF), the most common arrhythmia in clinical practice. Here, we tested …

Age is the dominant risk factor for most chronic human diseases, but the mechanisms
through which ageing confers this risk are largely unknown 1 . The age-related acquisition of …

Atrial fibrillation is a highly prevalent arrhythmia and a major risk factor for stroke, heart failure
and death 1 . We conducted a genome-wide association study (GWAS) in individuals of …

Late-breaking clinical trials presented at the annual scientific meetings of the ACC, AHA, HRS,
and European Society of Cardiology (2008 through 2010), as well as other selected data …

The National Heart, Lung, and Blood Institute convened an expert panel April 28 to 29, 2008,
to identify gaps and recommend research strategies to prevent atrial fibrillation (AF). The …

The drug-induced long QT syndrome is a distinct clinical entity that has evolved from an
electrophysiologic curiosity to a centerpiece in drug regulation and development. This evolution …

Importance SARS-CoV-2 infection is associated with persistent, relapsing, or new symptoms
or other health effects occurring after acute infection, termedpostacute sequelae of SARS-…