User profiles for Dean H. Kedes
 | Dean H. KedesUniversity of Virginia Verified email at virginia.edu Cited by 5791 |
[HTML][HTML] Sexual transmission and the natural history of human herpesvirus 8 infection
…, KA Page-Shafer, D Macrae, DH Kedes - … England Journal of …, 1998 - Mass Medical Soc
Background Although human herpesvirus 8 (HHV-8) has been suspected to be the etiologic
agent of Kaposi's sarcoma, little is known about its seroprevalence in the population, its …
agent of Kaposi's sarcoma, little is known about its seroprevalence in the population, its …
The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma–associated herpesvirus): distribution of infection in KS risk groups and evidence for sexual …
Striking differences in Kaposi's sarcoma (KS) risk for AIDS patients who acquire HIV via
homosexual activity and those whose HIV infections derive from blood product exposure suggest …
homosexual activity and those whose HIV infections derive from blood product exposure suggest …
Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapy.
DH Kedes, D Ganem - The Journal of clinical investigation, 1997 - Am Soc Clin Investig
Using a cell line (termed BCBL-1) derived from a peripheral effusion (body cavity-based)
lymphoma latently infected with Kaposi's sarcoma-associated herpesvirus (KSHV), we recently …
lymphoma latently infected with Kaposi's sarcoma-associated herpesvirus (KSHV), we recently …
Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus.
Over 85% of patients with Kaposi's sarcoma (KS) are seropositive for antibodies to the
latency-associated nuclear antigen (LANA) expressed in B cell lines infected with Kaposi's …
latency-associated nuclear antigen (LANA) expressed in B cell lines infected with Kaposi's …
[HTML][HTML] KSHV infects a subset of human tonsillar B cells, driving proliferation and plasmablast differentiation
…, TJ Ellison, DH Kedes - The Journal of clinical …, 2011 - Am Soc Clin Investig
Kaposi sarcoma–associated herpesvirus (KSHV; also known as HHV8) is the causative
agent of two B cell tumors, multicentric Castleman disease (MCD) and primary effusion …
agent of two B cell tumors, multicentric Castleman disease (MCD) and primary effusion …
[HTML][HTML] Rapamycin blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug
Background Infection with Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8) often
results in the development of fatal tumors in immunocompromised patients. Studies of renal …
results in the development of fatal tumors in immunocompromised patients. Studies of renal …
The Prevalence of Serum Antibody to Human Herpesvirus 8 (Kaposi Sarcoma—Associated Herpesvirus) Among HIV-Seropositive and High-Risk HIV-Seronegative …
DH Kedes, D Ganem, N Ameli, P Bacchetti… - Jama, 1997 - jamanetwork.com
Objective. —To determine the prevalence of human herpesvirus 8 (HHV-8) seropositivity
among women who are known to be infected with human immunodeficiency virus type 1 (HIV-1…
among women who are known to be infected with human immunodeficiency virus type 1 (HIV-1…
Capsid structure of Kaposi's sarcoma-associated herpesvirus, a gammaherpesvirus, compared to those of an alphaherpesvirus, herpes simplex virus type 1, and a …
The capsid of Kaposi's sarcoma-associated herpesvirus (KSHV) was visualized at 24-Å
resolution by cryoelectron microscopy. Despite limited sequence similarity between …
resolution by cryoelectron microscopy. Despite limited sequence similarity between …
[HTML][HTML] KSHV targets multiple leukocyte lineages during long-term productive infection in NOD/SCID mice
…, JR Taylor, D Camerini, DH Kedes - The Journal of …, 2006 - Am Soc Clin Investig
To develop an animal model of Kaposi sarcoma–associated herpesvirus (KSHV) infection
uniquely suited to evaluate longitudinal patterns of viral gene expression, cell tropism, and …
uniquely suited to evaluate longitudinal patterns of viral gene expression, cell tropism, and …
Surface downregulation of major histocompatibility complex class I, PE-CAM, and ICAM-1 following de novo infection of endothelial cells with Kaposi's sarcoma …
C Tomescu, WK Law, DH Kedes - Journal of virology, 2003 - Am Soc Microbiol
… phorbol 13-acetate and sodium butyrate for 12 h to initiate lytic replication and, after 3 days
(… DH Kedes, unpublished results]), cocultured these cells with adherent pDMVEC for 12 h in …
(… DH Kedes, unpublished results]), cocultured these cells with adherent pDMVEC for 12 h in …