User profiles for Deanne Taylor
Deanne M. Taylor PhDResearch Associate Professor, UPenn PSOM Verified email at upenn.edu Cited by 6387 |
[PDF][PDF] Powerful SNP-set analysis for case-control genome-wide association studies
GWAS have emerged as popular tools for identifying genetic variants that are associated
with disease risk. Standard analysis of a case-control GWAS involves assessing the …
with disease risk. Standard analysis of a case-control GWAS involves assessing the …
[HTML][HTML] Blastocyst biopsy with comprehensive chromosome screening and fresh embryo transfer significantly increases in vitro fertilization implantation and delivery …
Objective To determine whether blastocyst biopsy and rapid quantitative real-time polymerase
chain reaction (qPCR)–based comprehensive chromosome screening (CCS) improves in …
chain reaction (qPCR)–based comprehensive chromosome screening (CCS) improves in …
[HTML][HTML] In vitro fertilization with single euploid blastocyst transfer: a randomized controlled trial
EJ Forman, KH Hong, KM Ferry, X Tao, D Taylor… - Fertility and sterility, 2013 - Elsevier
OBJECTIVE: To determine whether performing comprehensive chromosome screening (CCS)
and transferring a single euploid blastocyst can result in an ongoing pregnancy rate that …
and transferring a single euploid blastocyst can result in an ongoing pregnancy rate that …
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral proteins bind to host
mitochondrial proteins, likely inhibiting oxidative phosphorylation (OXPHOS) and stimulating …
mitochondrial proteins, likely inhibiting oxidative phosphorylation (OXPHOS) and stimulating …
[PDF][PDF] Fundamental biological features of spaceflight: advancing the field to enable deep-space exploration
Research on astronaut health and model organisms have revealed six features of spaceflight
biology that guide our current understanding of fundamental molecular changes that occur …
biology that guide our current understanding of fundamental molecular changes that occur …
[HTML][HTML] A roadmap for the human developmental cell atlas
The Human Developmental Cell Atlas (HDCA) initiative, which is part of the Human Cell Atlas,
aims to create a comprehensive reference map of cells during development. This will be …
aims to create a comprehensive reference map of cells during development. This will be …
[HTML][HTML] Development and validation of an accurate quantitative real-time polymerase chain reaction–based assay for human blastocyst comprehensive chromosomal …
NR Treff, X Tao, KM Ferry, J Su, D Taylor, RT Scott Jr - Fertility and sterility, 2012 - Elsevier
OBJECTIVE: To develop and validate a quantitative real-time polymerase chain reaction (qPCR)–based
method for blastocyst trophectoderm comprehensive chromosome screening (…
method for blastocyst trophectoderm comprehensive chromosome screening (…
[HTML][HTML] Evaluation of targeted next-generation sequencing–based preimplantation genetic diagnosis of monogenic disease
OBJECTIVE: To investigate the applicability of next-generation sequencing (NGS) to
preimplantation genetic diagnosis (PGD); to evaluate semiconductor-based NGS for genetic …
preimplantation genetic diagnosis (PGD); to evaluate semiconductor-based NGS for genetic …
[PDF][PDF] Comprehensive multi-omics analysis reveals mitochondrial stress as a central biological hub for spaceflight impact
Spaceflight is known to impose changes on human physiology with unknown molecular
etiologies. To reveal these causes, we used a multi-omics, systems biology analytical approach …
etiologies. To reveal these causes, we used a multi-omics, systems biology analytical approach …
[HTML][HTML] What every reader should know about studies using electronic health record data but may be afraid to ask
Coincident with the tsunami of COVID-19–related publications, there has been a surge of
studies using real-world data, including those obtained from the electronic health record (EHR)…
studies using real-world data, including those obtained from the electronic health record (EHR)…