User profiles for Debasish Manna

Debasish Manna

Assistant Professor, IISER-Bhopal
Verified email at iiserb.ac.in
Cited by 1994

Light-controlled self-assembly of non-photoresponsive nanoparticles

…, H Zhao, M Börner, T Udayabhaskararao, D Manna… - Nature …, 2015 - nature.com
The ability to guide the assembly of nanosized objects reversibly with external stimuli, in
particular light, is of fundamental importance, and it contributes to the development of …

Reversible trapping and reaction acceleration within dynamically self-assembling nanoflasks

…, M Sawczyk, K Kučanda, D Manna… - Nature …, 2016 - nature.com
The chemical behaviour of molecules can be significantly modified by confinement to volumes
comparable to the dimensions of the molecules. Although such confined spaces can be …

Antithyroid drugs and their analogues: synthesis, structure, and mechanism of action

D Manna, G Roy, G Mugesh - Accounts of chemical research, 2013 - ACS Publications
Thyroid hormones are essential for the development and differentiation of all cells of the
human body. They regulate protein, fat, and carbohydrate metabolism. In this Account, we …

Synthesis, structure, spirocyclization mechanism, and glutathione peroxidase-like antioxidant activity of stable spirodiazaselenurane and spirodiazatellurane

BK Sarma, D Manna, M Minoura… - Journal of the American …, 2010 - ACS Publications
The first examples of stable spirodiazaselenurane and spirodiazatellurane were synthesized
by oxidative spirocyclization of the corresponding diaryl selenide and telluride and were …

Orthogonal light‐induced self‐assembly of nanoparticles using differently substituted azobenzenes

D Manna, T Udayabhaskararao, H Zhao… - Angewandte …, 2015 - Wiley Online Library
Precise control of the self‐assembly of selected components within complex mixtures is a
challenging goal whose realization is important for fabricating novel nanomaterials. Herein we …

Regioselective deiodination of thyroxine by iodothyronine deiodinase mimics: an unusual mechanistic pathway involving cooperative chalcogen and halogen bonding

D Manna, G Mugesh - Journal of the American Chemical Society, 2012 - ACS Publications
Iodothyronine deiodinases (IDs) are mammalian selenoenzymes that catalyze the conversion
of thyroxine (T4) to 3,5,3′-triiodothyronine (T3) and 3,3′,5′-triiodothyronine (rT3) by the …

Precision control of CRISPR-Cas9 using small molecules and light

SA Gangopadhyay, KJ Cox, D Manna, D Lim… - Biochemistry, 2019 - ACS Publications
The CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system is an
adaptive immune system of bacteria that has furnished several RNA-guided DNA …

Selenium‐Mediated Dehalogenation of Halogenated Nucleosides and its Relevance to the DNA Repair Pathway

S Mondal, D Manna, G Mugesh - … Chemie International Edition, 2015 - Wiley Online Library
Halogenated nucleosides can be incorporated into the newly synthesized DNA of replicating
cells and therefore are commonly used in the detection of proliferating cells in living tissues…

A Singular System with Precise Dosing and Spatiotemporal Control of CRISPR‐Cas9

D Manna, B Maji, SA Gangopadhyay… - Angewandte …, 2019 - Wiley Online Library
Several genome engineering applications of CRISPR‐Cas9, an RNA‐guided DNA endonuclease,
require precision control of Cas9 activity over dosage, timing, and targeted site in an …

[PDF][PDF] A chemical model for the inner-ring deiodination of thyroxine by iodothyronine deiodinase

D Manna, G Mugesh - Angew Chem Int Ed Engl, 2010 - academia.edu
Iodothyronine deiodinases (IDs) are mammalian selenoenzymes that play an important role
in the activation and inactivation of thyroid hormones.[1] The outer-ring (5’) deiodination of …