Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing
…, S Maiti, D Chakraborty - Proceedings of the …, 2019 - National Acad Sciences
Genome editing using the CRISPR/Cas9 system has been used to make precise heritable
changes in the DNA of organisms. Although the widely used Streptococcus pyogenes Cas9 (…
changes in the DNA of organisms. Although the widely used Streptococcus pyogenes Cas9 (…
[HTML][HTML] Selecting populations for non-analogous climate conditions using universal response functions: The case of Douglas-fir in central Europe
D Chakraborty, T Wang, K Andre, M Konnert, MJ Lexer… - PloS one, 2015 - journals.plos.org
Identifying populations within tree species potentially adapted to future climatic conditions is
an important requirement for reforestation and assisted migration programmes. Such …
an important requirement for reforestation and assisted migration programmes. Such …
Adapting Douglas-fir forestry in Central Europe: evaluation, application, and uncertainty analysis of a genetically based model
D Chakraborty, T Wang, K Andre, M Konnert… - European Journal of …, 2016 - Springer
Recommendations on suitable seed sources for reforestation are usually model based and
include uncertainties arising from model assumptions, parameter estimation, and future …
include uncertainties arising from model assumptions, parameter estimation, and future …
CRISPR/Cas9: a historical and chemical biology perspective of targeted genome engineering
The CRISPR–Cas9 system has revolutionized the process of making changes to the DNA
sequence of organisms. Relying on a simplistic model of RNA guided DNA binding and …
sequence of organisms. Relying on a simplistic model of RNA guided DNA binding and …
[HTML][HTML] Rapid and accurate nucleobase detection using FnCas9 and its application in COVID-19 diagnosis
Rapid detection of DNA/RNA pathogenic sequences or variants through point-of-care
diagnostics is valuable for accelerated clinical prognosis, as witnessed during the recent COVID-…
diagnostics is valuable for accelerated clinical prognosis, as witnessed during the recent COVID-…
FnCas9-based CRISPR diagnostic for rapid and accurate detection of major SARS-CoV-2 variants on a paper strip
… We thank all members of Chakraborty and Maiti labs for helpful discussions and valuable
insights. … Debojyoti Chakraborty: A patent application has been filed in relation to this work. (…
insights. … Debojyoti Chakraborty: A patent application has been filed in relation to this work. (…
Computational solar energy–Ensemble learning methods for prediction of solar power generation based on meteorological parameters in Eastern India
The challenges in applications of solar energy lies in its intermittency and dependency on
meteorological parameters such as; solar radiation, ambient temperature, rainfall, wind-speed …
meteorological parameters such as; solar radiation, ambient temperature, rainfall, wind-speed …
Rapid, field-deployable nucleobase detection and identification using FnCas9
Detection of pathogenic sequences or variants in DNA and RNA through a point-of-care
diagnostic approach is valuable for rapid clinical prognosis. In recent times, CRISPR based …
diagnostic approach is valuable for rapid clinical prognosis. In recent times, CRISPR based …
Rapid identification and tracking of SARS-CoV-2 variants of concern
The current vaccination campaign against SARS-CoV-2 has many challenging aspects, one
of which is maintaining the cold chain for the distribution, delivery, and storage of available …
of which is maintaining the cold chain for the distribution, delivery, and storage of available …
Identification of G-quadruplex structures in MALAT1 lncRNA that interact with nucleolin and nucleophosmin
Nuclear-retained long non-coding RNAs (lncRNAs) including MALAT1 have emerged as
critical regulators of many molecular processes including transcription, alternative splicing and …
critical regulators of many molecular processes including transcription, alternative splicing and …