We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS)
comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the …

Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…

Ulcerative colitis is a chronic inflammatory disease of the colon that presents as diarrhea
and gastrointestinal bleeding. We performed a genome-wide association study using DNA …

Inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn’s disease are
chronic, relapsing and remitting disorders of intestinal inflammation with potential systemic …

OBJECTIVES: In classifying Crohn's disease (CD) location, proximal (L4) disease includes
esophagogastroduodenal (EGD) and jejunal disease. Our aim was to determine the …

Crohn's disease (CD) is a complex disorder resulting from the interaction of intestinal
microbiota with the host immune system in genetically susceptible individuals. The largest meta-…

OBJECTIVE: Idiopathic intestinal pseudo-obstruction is characterized by the failure of the
intestinal tract to propel its contents appropriately. This leads to signs and symptoms of bowel …

Background Inflammatory bowel disease is a chronic inflammatory disorder of the gastrointestinal
tract that significantly impacts the health-related quality of life (HR-QOL). A decreased …

Background & Aims Genome-wide association studies have identified 200 inflammatory
bowel disease (IBD) loci, but the genetic architecture of Crohn’s disease (CD) and ulcerative …

Mycophenolate mofetil, an immunosuppressive agent, is frequently used following bone
marrow and solid organ transplantation. Diarrhea is a commonly seen side effect of …