Neuronal arborization is regulated by cell-autonomous and nonautonomous mechanisms
including endosomal signaling via BDNF/TrkB. The endosomal Na + /H + exchanger 6 (NHE6) …

Wnt1-expressing progenitors generate midbrain dopamine (MbDA) and cerebellum (Cb)
neurons in distinct temporal windows and from spatially discrete progenitor domains. It has …

Background Forging a relationship between progenitors with dynamically changing gene
expression and their terminal fate is instructive for understanding the logic of how cell-type …

Blubber has been used for decades to monitor exposure of marine mammals to persistent
organic pollutants (POPs). However, little is known about POP variability as a function of …

Conditional marking and gene inactivation experiments are valuable approaches used to
understand developmental and molecular mechanisms. CreER T is a fundamental component …

Midbrain dopamine (MbDA) neurons are partitioned into medial and lateral cohorts that control
complex functions. However, the genetic underpinnings of MbDA neuron heterogeneity …

Fate maps are generated by marking and tracking cells in vivo to determine how progenitors
contribute to specific structures and cell types in developing and adult tissue. An advance in …

A long-standing problem in development is understanding how progenitor cells transiently
expressing genes contribute to complex anatomical and functional structures. In the …

The National Institute of Standards and Technology (NIST) has prepared four seafood
reference materials (RMs) for use in food safety and nutrition studies: wild-caught and …

The cerebellum (Cb) is an exquisite structure that controls elaborate motor behaviors and is
essential for sensory-motor learning. During development, the Cb is derived from …