Neuregulins (NRGs) and their receptors, the ErbB protein tyrosine kinases, are essential for
neuronal development, but their functions in the adult CNS are unknown. We report that …

Regulation of postsynaptic glutamate receptors is one of the main mechanisms for altering
synaptic efficacy in the central nervous system. Recent studies have given insight into the …

Long-term potentiation (LTP) is an activity-dependent enhancement of synaptic efficacy,
considered a model of learning and memory. The biochemical cascade producing LTP requires …

The Cannabis plant has been used for many of years as a medicinal agent in the relief of
pain and seizures. It contains approximately 540 natural compounds including more than 100 …

The zebrafish is a popular model for developmental studies due to its accessibility by cellular,
molecular and genetic approaches. As a complement to these other methods, we have …

Children exposed to alcohol in utero have significantly delayed gross and fine motor skills,
as well as deficiencies in reflex development. The reasons that underlie the motor deficits …

Marijuana is one of the most commonly used illicit recreational drugs and is widely used for
medicinal purposes. The psychoactive ingredient in marijuana is ∆ 9 -tetrahydrocannabinol (…

Insect salivary glands are glands associated with nutrient intake whose secretions are
generally involved in the digestion and lubrication of food. They are under the control of …

In humans, mutations in electron transfer flavoprotein (ETF) or electron transfer flavoprotein
dehydrogenase (ETFDH) lead to MADD/glutaric aciduria type II, an autosomal recessively …

The function of the cellular prion protein (PrP C ) in healthy brains remains poorly understood,
in part because Prnp knockout mice are viable. On the other hand, transient knockdown of …