Use of molecular probes and PCR for detection and typing of Leishmania-a mini-review
W Degrave, O Fernandes, D Campbell… - Memórias do Instituto …, 1994 - SciELO Brasil
The use of molecular tools to detect and type Leishmania species in humans, reservoirs or
sandflies has been pursued using different approaches. The polymerase chain reaction …
sandflies has been pursued using different approaches. The polymerase chain reaction …
Problem‐based learning: Future challenges for educational practice and research
DHJM Dolmans, W De Grave… - Medical …, 2005 - Wiley Online Library
… Another interesting study focusing on the principle of constructive learning was conducted
by De Grave, Boshuizen and Schmidt,45 who investigated cognitive processes during …
by De Grave, Boshuizen and Schmidt,45 who investigated cognitive processes during …
Comparative Genomics of Two Leptospira interrogans Serovars Reveals Novel Insights into Physiology and Pathogenesis
Leptospira species colonize a significant proportion of rodent populations worldwide and
produce life-threatening infections in accidental hosts, including humans. Complete genome …
produce life-threatening infections in accidental hosts, including humans. Complete genome …
Zika virus evolution and spread in the Americas
…, I Lorenzana, J Cerbino-Neto, C Valim, W Degrave… - Nature, 2017 - nature.com
Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects
have attracted a great deal of attention 1 , 2 , much remains unknown about ZIKV disease …
have attracted a great deal of attention 1 , 2 , much remains unknown about ZIKV disease …
RATT: rapid annotation transfer tool
TD Otto, GP Dillon, WS Degrave… - Nucleic acids …, 2011 - academic.oup.com
Second-generation sequencing technologies have made large-scale sequencing projects
commonplace. However, making use of these datasets often requires gene function to be …
commonplace. However, making use of these datasets often requires gene function to be …
[HTML][HTML] In vitro and in vivo experimental models for drug screening and development for Chagas disease
…, SG Andrade, T Armstrong, W Degrave… - Memórias do Instituto …, 2010 - SciELO Brasil
Chagas disease, a neglected illness, affects nearly 12-14 million people in endemic areas
of Latin America. Although the occurrence of acute cases sharply has declined due to …
of Latin America. Although the occurrence of acute cases sharply has declined due to …
Sensitive detection and schizodeme classification of Trypanosoma cruzi cells by amplification of kinetoplast minicircle DNA sequences: use in diagnosis of Chagas' …
… nucleotide sequence of 20 minirepeat regions as determined by Degrave et al. (fig. 4 in
ref. … W. Zolg for communication of unpublished results, Dr. George Holz for supplying …
ref. … W. Zolg for communication of unpublished results, Dr. George Holz for supplying …
Use of PCR-mediated amplification of Mycobacterium leprae DNA in different types of clinical samples for the diagnosis of leprosy
…, EN Sarno, PN Suffys, WM Degrave - Journal of medical …, 1993 - microbiologyresearch.org
DNA of Mycobacterium leprae, obtained by a highly efficient nucleic acid extraction
procedure, was used for standardisation of the amplification of an M. leprae-specific repetitive …
procedure, was used for standardisation of the amplification of an M. leprae-specific repetitive …
Detection of Trypanosoma cruzi in blood specimens of chronic chagasic patients by polymerase chain reaction amplification of kinetoplast minicircle DNA: comparison …
…, O Thiemann, E De Paiva, W Degrave… - Journal of Clinical …, 1993 - Am Soc Microbiol
A panel of 114 blood samples from chronic chagasic patients and nonchagasic patients
was screened for Trypanosoma cruzi by xenodiagnostic, serologic, and polymerase chain …
was screened for Trypanosoma cruzi by xenodiagnostic, serologic, and polymerase chain …
A B-cell mitogen from a pathogenic trypanosome is a eukaryotic proline racemase
B Reina-San-Martin, W Degrave, C Rougeot… - Nature medicine, 2000 - nature.com
Lymphocyte polyclonal activation is a generalized mechanism of immune evasion among
pathogens. In a mouse model of Trypanosoma cruzi infection (American trypanosomiasis), …
pathogens. In a mouse model of Trypanosoma cruzi infection (American trypanosomiasis), …