[HTML][HTML] A deep investigation into the adipogenesis mechanism: Profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/β-catenin signaling …

…, Q Wang, S Xiao, A Li, Y Xie, J Li, X Zhao, Z He, D Mo - BMC genomics, 2010 - Springer
Background MicroRNAs (miRNAs) are a large class of tiny non-coding RNAs (~22-24 nt) that
regulate diverse biological processes at the posttranscriptional level by controlling mRNA …

[HTML][HTML] Comparative analyses by sequencing of transcriptomes during skeletal muscle development between pig breeds differing in muscle growth rate and fatness

X Zhao, D Mo, A Li, W Gong, S Xiao, Y Zhang, L Qin… - PloS one, 2011 - journals.plos.org
Understanding the dynamics of muscle transcriptome during development and between
breeds differing in muscle growth is necessary to uncover the complex mechanism underlying …

[HTML][HTML] Understanding PRRSV infection in porcine lung based on genome-wide transcriptome response identified by deep sequencing

S Xiao, J Jia, D Mo, Q Wang, L Qin, Z He, X Zhao… - PloS one, 2010 - journals.plos.org
Porcine reproductive and respiratory syndrome (PRRS) has been one of the most economically
important diseases affecting swine industry worldwide and causes great economic …

[HTML][HTML] Aberrant host immune response induced by highly virulent PRRSV identified by digital gene expression tag profiling

S Xiao, D Mo, Q Wang, J Jia, L Qin, X Yu, Y Niu, X Zhao… - BMC genomics, 2010 - Springer
Background There was a large scale outbreak of the highly pathogenic porcine reproductive
and respiratory syndrome (PRRS) in China and Vietnam during 2006 and 2007 that …

Lipopolysaccharide‐induced miR‐1224 negatively regulates tumour necrosis factor‐α gene expression by modulating Sp1

Y Niu, D Mo, L Qin, C Wang, A Li, X Zhao, X Wang… - …, 2011 - Wiley Online Library
The innate immune response provides the initial defence mechanism against infection by
other organisms. However, an excessive immune response will cause damage to host tissues. …

MicroRNA‐139‐5p suppresses 3T3‐L1 preadipocyte differentiation through notch and IRS1/PI3K/Akt insulin signaling pathways

…, Y Chen, X Zheng, Y Li, Q Zhang, D Mo… - Journal of cellular …, 2015 - Wiley Online Library
MicroRNAs (miRNAs) participate in the regulation of adipogenesis. Identification of the full
repertoire of miRNAs expressed in adipose tissue is likely to significantly improve our …

Analysis of reasons for sow culling and seasonal effects on reproductive disorders in Southern China

Y Zhao, X Liu, D Mo, Q Chen, Y Chen - Animal reproduction science, 2015 - Elsevier
Sow culling rates have a direct correlation to the economic efficiency of both breeding herd
and commercial herd. Analyzing the reasons of sow culling could lead to improve production …

[HTML][HTML] Integrative single-cell RNA-seq and ATAC-seq analysis of myogenic differentiation in pig

…, T Duo, Q Zhu, Z Liang, E Li, Y Chen, J Li, X Liu, D Mo - BMC biology, 2023 - Springer
Background Skeletal muscle development is a multistep process whose understanding is
central in a broad range of fields and applications, from the potential medical value to human …

Disruption of the ZBED6 binding site in intron 3 of IGF2 by CRISPR/Cas9 leads to enhanced muscle development in Liang Guang Small Spotted pigs

X Liu, H Liu, M Wang, R Li, J Zeng, D Mo, P Cong… - Transgenic …, 2019 - Springer
Insulin-like growth factor 2 (IGF2) plays an important role in the development of the foetus
and in post-natal growth and development. A SNP within intron 3 of porcine IGF2 disrupts a …

[HTML][HTML] Up-regulated miR-145 expression inhibits porcine preadipocytes differentiation by targeting IRS1

…, Y Zhang, Y Zhang, L Chen, D Mo - International Journal of …, 2012 - ncbi.nlm.nih.gov
Generally, most miRNAs that were up-regulated during differentiation promoted adipogenesis,
but our research indicated that up-regulation of miR-145 in porcine preadipocytes did not …