Bactericidal and intracellular activity of β-lactams against Mycobacterium abscessus

…, V Dubée, M Cortes, D Dorchêne… - Journal of …, 2016 - academic.oup.com
Objectives Cefoxitin and imipenem are the sole recommended β-lactams for the treatment
of Mycobacterium abscessus pulmonary infections. Here, we investigated whether one of …

Role of endopeptidases in peptidoglycan synthesis mediated by alternative cross‐linking enzymes in Escherichia coli

H Voedts, D Dorchêne, A Lodge, W Vollmer… - The EMBO …, 2021 - embopress.org
Bacteria resist to the turgor pressure of the cytoplasm through a net‐like macromolecule, the
peptidoglycan, made of glycan strands connected via peptides cross‐linked by penicillin‐…

Ceftazidime-Avibactam Resistance Mediated by the N346Y Substitution in Various AmpC β-Lactamases

…, A Debray, P Adjadj, D Dorchêne… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
Chromosomal and plasmid-borne AmpC cephalosporinases are a major resistance
mechanism to β-lactams in Enterobacteriaceae and Pseudomonas aeruginosa . The new β-…

Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis

…, G Schepers, D Dorchêne… - Nucleic Acids …, 2022 - academic.oup.com
Xenobiotic nucleic acids (XNAs) offer tremendous potential for synthetic biology, biotechnology,
and molecular medicine but their ability to mimic nucleic acids still needs to be explored. …

[PDF][PDF] Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis

D Dorchêne, L Iannazzo, D Patin… - Nucleic Acids …, 2022 - hal.sorbonne-universite.fr
Xenobiotic nucleic acids (XNAs) offer tremendous potential for synthetic biology, biotechnology,
and molecular medicine but their ability to mimic nucleic acids still needs to be explored. …

In vitro activity of tedizolid against the Mycobacterium abscessus complex

F Compain, D Soroka, B Heym, JL Gaillard… - … and infectious disease, 2018 - Elsevier
Infections due to Mycobacterium abscessus carry a poor prognosis since this rapidly growing
mycobacterium is intrinsically resistant to most antibiotics. Here, we evaluate the in vitro …

[HTML][HTML] Enterobacterales carrying chromosomal AmpC β-lactamases in Europe (EuESCPM): Epidemiology and antimicrobial resistance burden from a cohort of 27 …

M Boattini, G Bianco, LI Llorente, LA Acero… - International Journal of …, 2024 - Elsevier
Introduction The ESCPM group (Enterobacter species including Klebsiella aerogenes -
formerly Enterobacter aerogenes, Serratia species, Citrobacter freundii complex, Providencia …

Distinct pathways for modification of the bacterial cell wall by non‐canonical d‐amino acids

F Cava, MA De Pedro, H Lam, BM Davis… - The EMBO …, 2011 - embopress.org
Production of non‐canonical d‐amino acids (NCDAAs) in stationary phase promotes remodelling
of peptidoglycan (PG), the polymer that comprises the bacterial cell wall. Impairment of …

Evolutionary potential, cross‐stress behavior and the genetic basis of acquired stress resistance in Escherichia coli

M Dragosits, V Mozhayskiy… - Molecular systems …, 2013 - embopress.org
Bacterial populations have a remarkable capacity to cope with extreme environmental
fluctuations in their natural environments. In certain cases, adaptation to one stressful …

Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi‐enzyme complexes in Escherichia coli

M Banzhaf, HCL Yau, J Verheul, A Lodge… - The EMBO …, 2020 - embopress.org
The peptidoglycan ( PG ) sacculus provides bacteria with the mechanical strength to maintain
cell shape and resist osmotic stress. Enlargement of the mesh‐like sacculus requires the …