The SARS-CoV-2 proteome shares regions of conservation with endemic human coronaviruses
(CoVs), but it remains unknown to what extent these may be cross-recognized by the …

Viral diseases are one of the leading causes of morbidity and mortality in the world. Virus-specific
vaccines and antiviral drugs are the most powerful tools to combat viral diseases. …

As of June 2020, the number of people infected with severe acute respiratory coronavirus 2 (SARS-CoV-2)
continues to skyrocket, with more than 6.7 million cases worldwide. Both the …

Human influenza A viruses (IAVs) cause global pandemics and epidemics, which remain
serious threats to public health because of the shortage of effective means of control. To …

With the increasing pace of global warming, it is important to understand the role of
meteorological factors in influenza virus (IV) epidemics. In this study, we investigated the impact of …

Hepatotropic viruses naturally have narrow host and tissue tropisms, challenging the development
of robust experimental models. The advent of organoid technology provides a unique …

Many viruses package their genome into preformed capsids using packaging motors
powered by the hydrolysis of ATP. The hexameric ATPase P4 of dsRNA bacteriophage φ12, …

Therapeutic options for coronaviruses remain limited. To address this unmet medical need,
we screened 5406 compounds, including United States Food and Drug Administration (FDA)-…

An epidemic of Zika virus (ZIKV) infection associated with congenital abnormalities such as
microcephaly, is ongoing in the Americas and the Pacific. Currently there are no approved …

Viruses are the major causes of acute and chronic infectious diseases in the world. According
to the World Health Organization, there is an urgent need for better control of viral diseases…