The molecular basis of X-linked recessive anhidrotic ectodermal dysplasia with immunodeficiency
(EDA-ID) has remained elusive. Here we report hypomorphic mutations in the gene …

Members of the tumour-necrosis factor receptor (TNFR) family that contain an intracellular
death domain initiate signalling by recruiting cytoplasmic death domain adapter proteins 1 , 2 . …

X-linked hypohidrotic ectodermal dysplasia results in abnormal morphogenesis of teeth,
hair and eccrine sweat glands 1. The gene (ED1) responsible for the disorder has been …

Although inductive interactions are known to be essential for specification of cell fate in many
vertebrate tissues, the signals and receptors responsible for transmitting this information …

Hair follicles are spaced apart from one another at regular intervals through the skin.
Although follicles are predominantly epidermal structures, classical tissue recombination …

Hair follicles have been observed to provide a major cellular contribution to epidermal healing,
with emigration of stem-derived cells from the follicles aiding in wound reepithelialization. …

tabby and downless mutant mice have apparently identical defects in teeth, hair and sweat
glands. Recently, genes responsible for these spontaneous mutations have been identified. …

Hair morphology differs dramatically between human populations: people of East Asian
ancestry typically have a coarse hair texture, with individual fibers being straight, of large …

Fingerprints are complex and individually unique patterns in the skin. Established prenatally,
the molecular and cellular mechanisms that guide fingerprint ridge formation and their …

Two theories address the origin of repeating patterns, such as hair follicles, limb digits, and
intestinal villi, during development. The Turing reaction–diffusion system posits that …