Muscle-invasive bladder cancer (MIBC) is an aggressive disease with limited therapeutic
options. PD-1 pathway targeting immunotherapies have been approved to treat advanced …

Over the past 20 years since its introduction, Kosteletzkya virginica has proved to be one of
the optimal halophytes for saline land restoration in China. In six seashore mallow plantations…

The thermophilic filamentous fungus Talaromyces emersonii secretes a variety of hydrolytic
enzymes that are of interest for processing of biomass into fuel. Many carbohydrases have …

Purpose The objective of this study was to describe trends in the prevalence of regular aspirin
and nonsteroidal anti‐inflammatory drug (NSAID) use among adults in the United States …

The bacterial pathogens of the genus Yersinia, the causative agents of plague, septicemia,
and gastrointestinal syndromes, use a type III secretion system to inject virulence factors into …

Precision medicine is part of the logical evolution of contemporary evidence-based medicine
that seeks to reduce errors and optimize outcomes when making medical decisions and …

Calorie restriction, without malnutrition, has been shown to increase lifespan and is associated
with a shift away from glycolysis toward beta-oxidation. The objective of this study was to …

The protease fibroblast activation protein (FAP) is a specific marker of activated mesenchymal
cells in tumour stroma and fibrotic liver. A specific, reliable FAP enzyme assay has been …

… Lysates were incubated at 70 C for 1 h and cooled on ice prior to adding 500 μl of 0.5 M
HCl. A 60 μl aliquot of neutralized lysates was removed for protein quantitation using the …

The impact of COVID-19-related stress on perinatal women is of heightened public health
concern given the established intergenerational impact of maternal stress-exposure on infants …