User profiles for Dennis S Mackin

Dennis Mackin

Medical Physicist, MD Anderson Cancer Center
Verified email at mdanderson.org
Cited by 25769

Imaging of prompt gamma rays emitted during delivery of clinical proton beams with a Compton camera: feasibility studies for range verification

…, S Avery, DS Mackin, S Beddar - Physics in Medicine & …, 2015 - iopscience.iop.org
The purpose of this paper is to evaluate the ability of a prototype Compton camera (CC) to
measure prompt gamma rays (PG) emitted during delivery of clinical proton pencil beams for …

[HTML][HTML] Comprehensive investigation on controlling for CT imaging variabilities in radiomics studies

…, RM Howell, H Li, RJ Stafford, LE Court, DS Mackin - Scientific reports, 2018 - nature.com
Radiomics has shown promise in improving models for predicting patient outcomes. However,
to maximize the information gain of the radiomics features, especially in larger patient …

[HTML][HTML] Lung tumor segmentation methods: impact on the uncertainty of radiomics features for non-small cell lung cancer

…, CB Peterson, C Tang, EJ Koay, W Yu, DS Mackin… - PLoS …, 2018 - journals.plos.org
Purpose To evaluate the uncertainty of radiomics features from contrast-enhanced breath-hold
helical CT scans of non-small cell lung cancer for both manual and semi-automatic …

Measurement of characteristic prompt gamma rays emitted from oxygen and carbon in tissue-equivalent samples during proton beam irradiation

JC Polf, R Panthi, DS Mackin… - Physics in Medicine …, 2013 - iopscience.iop.org
The purpose of this work was to characterize how prompt gamma (PG) emission from tissue
changes as a function of carbon and oxygen concentration, and to assess the feasibility of …

Imaging-genomic study of head and neck squamous cell carcinoma: associations between radiomic phenotypes and genomic mechanisms via integration of the …

…, H Elhalawani, H Skinner, DS Mackin… - JCO clinical cancer …, 2019 - ascopubs.org
Purpose Recent data suggest that imaging radiomic features of a tumor could be indicative
of important genomic biomarkers. Understanding the relationship between radiomic and …

Practical guidelines for handling head and neck computed tomography artifacts for quantitative image analysis

RB Ger, DF Craft, DS Mackin, S Zhou… - … Medical Imaging and …, 2018 - Elsevier
Radiomics studies have demonstrated the potential use of quantitative image features to
improve prognostic stratification of patients with head and neck cancer. Imaging protocol …

[HTML][HTML] Applications of machine learning to improve the clinical viability of Compton camera based in vivo range verification in proton radiotherapy

…, CA Barajas, SW Peterson, DS Mackin, S Beddar… - Frontiers in …, 2022 - frontiersin.org
We studied the application of a deep, fully connected Neural Network (NN) to process prompt
gamma (PG) data measured by a Compton camera (CC) during the delivery of clinical …

[HTML][HTML] Machine learning applications in head and neck radiation oncology: lessons from open-source radiomics challenges

…, GE Marai, D Vock, SY Lai, DS Mackin… - Frontiers in …, 2018 - frontiersin.org
Radiomics leverages existing image datasets to provide non-visible data extraction via image
post-processing, with the aim of identifying prognostic, and predictive imaging features at …

Prognostic value of combining a quantitative image feature from positron emission tomography with clinical factors in oligometastatic non-small cell lung cancer

…, CM Yost, DS Mackin, DV Fried, S Zhou… - Radiotherapy and …, 2018 - Elsevier
Background and purpose Oligometastatic non-small cell lung cancer (NSCLC) is a heterogeneous
condition with few known risk stratification factors. A quantitative imaging feature (QIF…

Guidelines and experience using imaging biomarker explorer (IBEX) for radiomics

…, BM Anderson, J Yang, DS Mackin… - JoVE (Journal of …, 2018 - jove.com
Imaging Biomarker Explorer (IBEX) is an open-source tool for medical imaging radiomics
work. The purpose of this paper is to describe how to use IBEX's graphical user interface (GUI) …