A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice
In contrast to lower vertebrates, the mammalian heart has limited capacity to regenerate after
injury in part due to ineffective reactivation of cardiomyocyte proliferation. We show that the …
injury in part due to ineffective reactivation of cardiomyocyte proliferation. We show that the …
[HTML][HTML] Plasticity of Hopx+ type I alveolar cells to regenerate type II cells in the lung
…, LJ Manderfield, M Gupta, D Li, L Li… - Nature …, 2015 - nature.com
The plasticity of differentiated cells in adult tissues undergoing repair is an area of intense
research. Pulmonary alveolar type II cells produce surfactant and function as progenitors in …
research. Pulmonary alveolar type II cells produce surfactant and function as progenitors in …
Effects of flow shear stress and mass transport on the construction of a large-scale tissue-engineered bone in a perfusion bioreactor
D Li, T Tang, J Lu, K Dai - Tissue Engineering Part A, 2009 - liebertpub.com
Currently, a tissue-engineered bone is usually constructed using a perfusion bioreactor in
vitro. In the perfusion culture, fluid flow can exert shear stress on the cells seeded on scaffold, …
vitro. In the perfusion culture, fluid flow can exert shear stress on the cells seeded on scaffold, …
Integration of Bmp and Wnt signaling by Hopx specifies commitment of cardiomyoblasts
R Jain, D Li, M Gupta, LJ Manderfield, JL Ifkovits… - Science, 2015 - science.org
INTRODUCTION Cardiac progenitor cells are multipotent, and lineage analyses of murine
and chick cardiac development have demonstrated that these cells give rise to the cardiac …
and chick cardiac development have demonstrated that these cells give rise to the cardiac …
[HTML][HTML] Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction
V Ramjee, D Li, LJ Manderfield, F Liu… - The Journal of …, 2017 - Am Soc Clin Investig
Ischemic heart disease resulting from myocardial infarction (MI) is the most prevalent form of
heart disease in the United States. Post-MI cardiac remodeling is a multifaceted process …
heart disease in the United States. Post-MI cardiac remodeling is a multifaceted process …
Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inheritable myocardial disorder
associated with fibrofatty replacement of myocardium and ventricular arrhythmia. A subset …
associated with fibrofatty replacement of myocardium and ventricular arrhythmia. A subset …
Circulating exosomes derived from transplanted progenitor cells aid the functional recovery of ischemic myocardium
The stem cell field is hindered by its inability to noninvasively monitor transplanted cells
within the target organ in a repeatable, time-sensitive, and condition-specific manner. We …
within the target organ in a repeatable, time-sensitive, and condition-specific manner. We …
Discovery of active components in herbs using chromatographic separation coupled with online bioassay
L De-Qiang, J Zhao, D Wu, L Shao-Ping - Journal of Chromatography B, 2016 - Elsevier
Discovery of bioactive compounds from complex mixtures is a challenge. In past decades,
several strategies were developed and implemented for rapid and effective screening and …
several strategies were developed and implemented for rapid and effective screening and …
Adversarial deep ensemble: Evasion attacks and defenses for malware detection
Malware remains a big threat to cyber security, calling for machine learning based malware
detection. While promising, such detectors are known to be vulnerable to evasion attacks. …
detection. While promising, such detectors are known to be vulnerable to evasion attacks. …
Recent advances in thermal conductivity and thermal applications of graphene and its derivatives nanofluids
H Lin, Q Jian, X Bai, D Li, Z Huang, W Huang… - Applied Thermal …, 2023 - Elsevier
With the rapid development of industrial technology, more and more high-power-consumption
devices are utilized, resulting in significant challenges to the durability, reliability, and …
devices are utilized, resulting in significant challenges to the durability, reliability, and …