User profiles for Devasena Ponnalagu

Devasena ponnalagu

Assistant Professor, University of Washington
Verified email at uw.edu
Cited by 750

[HTML][HTML] Early gestational mesenchymal stem cell secretome attenuates experimental bronchopulmonary dysplasia in part via exosome-associated factor TSG-6

S Chaubey, S Thueson, D Ponnalagu, MA Alam… - Stem cell research & …, 2018 - Springer
Background Mesenchymal stem cells (MSCs) are promising tools for the treatment of human
lung disease and other pathologies relevant to newborn medicine. Recent studies have …

Anion channels of mitochondria

D Ponnalagu, H Singh - Pharmacology of Mitochondria, 2017 - Springer
Mitochondria are the “power house” of a cell continuously generating ATP to ensure its
proper functioning. The constant production of ATP via oxidative phosphorylation demands a …

Molecular identity of cardiac mitochondrial chloride intracellular channel proteins

D Ponnalagu, SG Rao, J Farber, W Xin, AT Hussain… - Mitochondrion, 2016 - Elsevier
Emerging evidences demonstrate significance of chloride channels in cardiac function and
cardioprotection from ischemia–reperfusion (IR) injury. Unlike mitochondrial potassium …

CLIC4 localizes to mitochondrial-associated membranes and mediates cardioprotection

D Ponnalagu, S Hamilton, S Sanghvi, D Antelo… - Science …, 2022 - science.org
Mitochondrial-associated membranes (MAMs) are known to modulate organellar and cellular
functions and can subsequently affect pathophysiology including myocardial ischemia-…

[HTML][HTML] Genetic strain and sex differences in a hyperoxia-induced mouse model of varying severity of bronchopulmonary dysplasia

S Leary, P Das, D Ponnalagu, H Singh… - The American journal of …, 2019 - Elsevier
Bronchopulmonary dysplasia (BPD) is a disease prevalent in preterm babies with a need
for supplemental oxygen, resulting in impaired lung development and dysregulated …

[HTML][HTML] Expression and Activation of BKCa Channels in Mice Protects Against Ischemia-Reperfusion Injury of Isolated Hearts by Modulating Mitochondrial Function

SK Goswami, D Ponnalagu, AT Hussain… - Frontiers in …, 2019 - frontiersin.org
Aims: Activation and expression of large conductance calcium and voltage-activated potassium
channel (BK Ca ) by pharmacological agents have been implicated in cardioprotection …

Three decades of chloride intracellular channel proteins: from organelle to organ physiology

S Gururaja Rao, D Ponnalagu… - Current protocols in …, 2018 - Wiley Online Library
Intracellular organelles are membranous structures central for maintaining cellular physiology
and the overall health of the cell. To maintain cellular function, intracellular organelles are …

Novel biomarkers of bronchopulmonary dysplasia and bronchopulmonary dysplasia-associated pulmonary hypertension

…, B Yeboah, P Das, D Shah, D Ponnalagu… - Journal of …, 2020 - nature.com
Objective To quantify and compare levels of potential biomarkers in neonates with (i)
Bronchopulmonary dysplasia (BPD); (ii) BPD-associated pulmonary hypertension (BPD-PH); (iii) …

New water-soluble oxyamino chitosans as biocompatible vectors for efficacious anticancer therapy via co-delivery of gene and drug

M Kamra, P Moitra, D Ponnalagu… - … applied materials & …, 2019 - ACS Publications
Among the many nonviral gene delivery vectors, chitosan, being a polysaccharide of natural
origin, has gained special importance. In this report, chitosan (CS) has been solubilized in …

Measurement of oxidative stress markers in vitro using commercially available kits

B Gardiner, JA Dougherty, D Ponnalagu… - Measuring Oxidants and …, 2020 - Springer
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are highly reactive
molecules, with significant effects in human diseases including cancer and cardiovascular …