The robust specification of organ development depends on coordinated cell-cell communication.
This process requires signal integration among multiple pathways, relying on second …

Information flow within and between cells depends significantly on calcium (Ca 2+ ) signaling
dynamics. However, the biophysical mechanisms that govern emergent patterns of Ca 2+ …

Background G proteins mediate cell responses to various ligands and play key roles in
organ development. Dysregulation of G-proteins or Ca 2+ signaling impacts many human …

Abstract Information flow within and between cells depends in part on calcium (Ca 2+ ) signaling
dynamics. However, the biophysical mechanisms that govern emergent patterns of Ca 2…

Organ development is driven by a set of patterned inductive signals. However, how these
signals are integrated to coordinate tissue patterning is still poorly understood. Calcium ions (…

Abstract Development of fully functional organs from undifferentiated cells requires constant
communication between various participating cells. An important component in this cellular …

Phenomics requires quantification of large volumes of image data, necessitating high
throughput image processing approaches. Existing image processing pipelines for Drosophila …

… Francisco Huizar and Dharsan Soundarrajan contributed equally to this work. … with a
nonlinear degradation profile (k 1 ), a source term dependent upon location (k 2 ), and effective …

… Dharsan Soundarrajan … David and Dharsan Soundarrajan contributed reagents/materials/analysis
tools; … Hanot CC, Choi YS, Anani TB, Soundarrajan D, David AE. Effects of Iron-Oxide …

Organ development relies on a symphony of signals that are coordinated spatiotemporally.
Emerging research has implicated neurotransmitter receptors, belonging to the GPCR …