User profiles for Diana Piol

Diana Piol

VIB-KU Leuven
Verified email at kuleuven.be
Cited by 100

Lost in local translation: TDP-43 and FUS in axonal/neuromuscular junction maintenance and dysregulation in amyotrophic lateral sclerosis

D Piol, T Robberechts, S Da Cruz - Neuron, 2023 - cell.com
Key early features of amyotrophic lateral sclerosis (ALS) are denervation of neuromuscular
junctions and axonal degeneration. Motor neuron homeostasis relies on local translation …

Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy

MJ Polanco, S Parodi, D Piol, C Stack… - Science Translational …, 2016 - science.org
Spinobulbar muscular atrophy (SBMA) is an X-linked neuromuscular disease caused by
polyglutamine (polyQ) expansion in the androgen receptor (AR) gene. SBMA belongs to the …

[HTML][HTML] Polyglutamine-expanded androgen receptor alteration of skeletal muscle homeostasis and myonuclear aggregation are affected by sex, age and muscle …

M Chivet, C Marchioretti, M Pirazzini, D Piol… - Cells, 2020 - mdpi.com
Polyglutamine (polyQ) expansions in the androgen receptor (AR) gene cause spinal and
bulbar muscular atrophy (SBMA), a neuromuscular disease characterized by lower motor …

Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function

D Piol, L Tosatto, E Zuccaro, EN Anderson… - Science …, 2023 - science.org
Spinal and bulbar muscular atrophy is caused by polyglutamine (polyQ) expansions in
androgen receptor (AR), generating gain-of-function toxicity that may involve phosphorylation. …

[HTML][HTML] Motor neuron diseases and neuroprotective peptides: A closer look to neurons

E Zuccaro, D Piol, M Basso, M Pennuto - Frontiers in Aging …, 2021 - frontiersin.org
Motor neurons (MNs) are specialized neurons responsible for muscle contraction that
specifically degenerate in motor neuron diseases (MNDs), such as amyotrophic lateral sclerosis (…

[HTML][HTML] Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation

…, S Megat, S Dirrig-Grosch, G Picchiarelli, D Piol… - Molecular …, 2021 - Springer
Mutations in FUS, an RNA-binding protein involved in multiple steps of RNA metabolism, are
associated with the most severe forms of amyotrophic lateral sclerosis (ALS). Accumulation …

Project Emery: Humanizing Patient Experience through Arts Expressive Activity among Clinically Isolated Patients in a Large Referral Hospital in Qatar

…, AV Capaspas, J Mulla, BS Zu'bi, E Swallmeh, DL Piol… - 2022 - researchsquare.com
Project Emery is a project and a strategy aimed to humanize the patient experience at Hamad
General Hospital (HGH), which emphasized the need to translate compassionate and safe …

Physiological and pathological role of serine 96 phosphorylation in the regulation of androgen receptor

D Piol - 2018 - eprints-phd.biblio.unitn.it
Spinal and bulbar muscular atrophy (SBMA) is an X-linked neuromuscular disorder characterized
by the progressive dysfunction and loss of lower motor neurons. SBMA is caused by …

Improvement of laboratory skills of Chemical and Civil Engineering students using an interdisciplinary service-learning project for water quality and supply assessment …

MN Piol, A Saralegui, G Orero… - FEMS microbiology …, 2019 - academic.oup.com
The University of Buenos Aires (UBA) develops the UBANEX program, focused on service-learning
projects for students involving social, environmental and public health concerns. One …

Dolomite used in phosphate water treatment: Desorption processes, recovery, reuse and final disposition

MN Piol, M Paricoto, AB Saralegui, S Basack… - Journal of environmental …, 2019 - Elsevier
Desorption is a method that contributes to two important aspects for the sustainability of the
water treatments that involve adsorption processes: a) the regeneration of the adsorbent …