Active learning narrows achievement gaps for underrepresented students in undergraduate science, technology, engineering, and math
…, S Behling, N Chambwe, DL Cintrón… - Proceedings of the …, 2020 - National Acad Sciences
We tested the hypothesis that underrepresented students in active-learning classrooms
experience narrower achievement gaps than underrepresented students in traditional lecturing …
experience narrower achievement gaps than underrepresented students in traditional lecturing …
Molecular basis of flowering under natural long-day conditions in Arabidopsis
…, MF Covington, N Lee, ER Taagen, D Laboy Cintrón… - Nature Plants, 2018 - nature.com
Plants sense light and temperature changes to regulate flowering time. Here, we show that
expression of the Arabidopsis florigen gene, FLOWERING LOCUS T (FT), peaks in the …
expression of the Arabidopsis florigen gene, FLOWERING LOCUS T (FT), peaks in the …
[HTML][HTML] TCP4-dependent induction of CONSTANS transcription requires GIGANTEA in photoperiodic flowering in Arabidopsis
…, GS Goralogia, MS Kwon, D Laboy Cintrón… - PLoS …, 2017 - journals.plos.org
Photoperiod is one of the most reliable environmental cues for plants to regulate flowering
timing. In Arabidopsis thaliana, CONSTANS (CO) transcription factor plays a central role in …
timing. In Arabidopsis thaliana, CONSTANS (CO) transcription factor plays a central role in …
[HTML][HTML] TANGO2: expanding the clinical phenotype and spectrum of pathogenic variants
…, K Golden-Grant, A LaCroix, AM Muir, DL Cintrón… - Genetics in …, 2019 - nature.com
Purpose TANGO2-related disorders were first described in 2016 and prior to this publication,
only 15 individuals with TANGO2-related disorder were described in the literature. Primary …
only 15 individuals with TANGO2-related disorder were described in the literature. Primary …
[PDF][PDF] Machine learning dissection of human accelerated regions in primate neurodevelopment
…, M Kircher, B Martin, B Alvarado, O Elor, DL Cintron… - Neuron, 2023 - cell.com
Using machine learning (ML), we interrogated the function of all human-chimpanzee variants
in 2,645 human accelerated regions (HARs), finding 43% of HARs have variants with large …
in 2,645 human accelerated regions (HARs), finding 43% of HARs have variants with large …
[PDF][PDF] A recurrent, de novo pathogenic variant in ARPC4 disrupts actin filament formation and causes microcephaly and speech delay
DL Cintron, AM Muir, A Scott, M McDonald… - Human Genetics and …, 2022 - cell.com
We report seven affected individuals from six families with a recurrent, de novo variant in the
ARPC4 gene (c.472C>T [p.Arg158Cys (GenBank: NM_005718.4)]). Core features in …
ARPC4 gene (c.472C>T [p.Arg158Cys (GenBank: NM_005718.4)]). Core features in …
Leveraging sequences missing from the human genome to diagnose cancer
Cancer diagnosis using cell-free DNA (cfDNA) has potential to improve treatment and
survival but has several technical limitations. Here, we show that tumor-associated mutations …
survival but has several technical limitations. Here, we show that tumor-associated mutations …
Integrative single-cell characterization of hypothalamus sex-differential and obesity-associated genes and regulatory elements
Over 500 noncoding genomic loci are associated with obesity. The majority of these loci reside
near genes that are expressed in the hypothalamus in specific neuronal subpopulations …
near genes that are expressed in the hypothalamus in specific neuronal subpopulations …
Correction: TANGO2: expanding the clinical phenotype and spectrum of pathogenic variants
…, A LaCroix, AM Muir, DL Cintrón… - Genetics in …, 2019 - gimjournal.org
The original version of this Article contained an error in the spelling of the author J.
Lawrence Merritt, which was incorrectly given as Lawrence Merritt. This has now been …
Lawrence Merritt, which was incorrectly given as Lawrence Merritt. This has now been …
[HTML][HTML] Exploring the Transporters Dynamics in Blood-Brain Barrier Functionality and Innovative Treatments for Non-Alcoholic Fatty Liver Disease/Steatohepatitis
X Zhou - 2024 - escholarship.org
This dissertation presents a multifaceted study exploring critical aspects of drug development,
focusing on the transporters on Blood-Brain Barrier (BBB) and a novel approach for Non-…
focusing on the transporters on Blood-Brain Barrier (BBB) and a novel approach for Non-…