[HTML][HTML] The genetic architecture of structural left–right asymmetry of the human brain
Left–right hemispheric asymmetry is an important aspect of healthy brain organization for many
functions including language, and it can be altered in cognitive and psychiatric disorders. …
functions including language, and it can be altered in cognitive and psychiatric disorders. …
Mapping brain asymmetry in health and disease through the ENIGMA consortium
…, SR Mathias, D Van Rooij, D Schijven… - Human brain …, 2022 - Wiley Online Library
Left–right asymmetry of the human brain is one of its cardinal features, and also a complex,
multivariate trait. Decades of research have suggested that brain asymmetry may be altered …
multivariate trait. Decades of research have suggested that brain asymmetry may be altered …
Handedness and its genetic influences are associated with structural asymmetries of the cerebral cortex in 31,864 individuals
Z Sha, A Pepe, D Schijven… - Proceedings of the …, 2021 - National Acad Sciences
Roughly 10% of the human population is left-handed, and this rate is increased in some
brain-related disorders. The neuroanatomical correlates of hand preference have remained …
brain-related disorders. The neuroanatomical correlates of hand preference have remained …
[HTML][HTML] International meta-analysis of PTSD genome-wide association studies identifies sex-and ancestry-specific genetic risk loci
…, NL Saccone, SE Sanchez, D Schijven… - Nature …, 2019 - nature.com
The risk of posttraumatic stress disorder (PTSD) following trauma is heritable, but robust
common variants have yet to be identified. In a multi-ethnic cohort including over 30,000 PTSD …
common variants have yet to be identified. In a multi-ethnic cohort including over 30,000 PTSD …
[HTML][HTML] Patterns of brain asymmetry associated with polygenic risks for autism and schizophrenia implicate language and executive functions but not brain …
Autism spectrum disorder (ASD) and schizophrenia have been conceived as partly opposing
disorders in terms of systemizing vs. empathizing cognitive styles, with resemblances to …
disorders in terms of systemizing vs. empathizing cognitive styles, with resemblances to …
Comprehensive pathway analyses of schizophrenia risk loci point to dysfunctional postsynaptic signaling
D Schijven, D Kofink, V Tragante, M Verkerke… - Schizophrenia …, 2018 - Elsevier
Large-scale genome-wide association studies (GWAS) have implicated many low-penetrance
loci in schizophrenia. However, its pathological mechanisms are poorly understood, …
loci in schizophrenia. However, its pathological mechanisms are poorly understood, …
[HTML][HTML] Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
RL McLaughlin, D Schijven, W Van Rheenen… - Nature …, 2017 - nature.com
We have previously shown higher-than-expected rates of schizophrenia in relatives of patients
with amyotrophic lateral sclerosis (ALS), suggesting an aetiological relationship between …
with amyotrophic lateral sclerosis (ALS), suggesting an aetiological relationship between …
Genetic architecture of the white matter connectome of the human brain
White matter tracts form the structural basis of large-scale brain networks. We applied brain-wide
tractography to diffusion images from 30,810 adults (UK Biobank) and found significant …
tractography to diffusion images from 30,810 adults (UK Biobank) and found significant …
Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium
D Schijven, MC Postema… - Proceedings of the …, 2023 - National Acad Sciences
Left–right asymmetry is an important organizing feature of the healthy brain that may be
altered in schizophrenia, but most studies have used relatively small samples and …
altered in schizophrenia, but most studies have used relatively small samples and …
Mid‐pregnancy corticotropin‐releasing hormone levels in association with postpartum depressive symptoms
…, C Hellgren, JD Olivier, D Schijven… - Depression and …, 2016 - Wiley Online Library
Background Peripartum depression is a common cause of pregnancy‐ and postpartum‐related
morbidity. The production of corticotropin‐releasing hormone (CRH) from the placenta …
morbidity. The production of corticotropin‐releasing hormone (CRH) from the placenta …