Cortical function can be shaped by sensory experience during a critical period. The onset of
the critical period is thought to coincide with the onset of thalamocortical transmission to the …

The cerebellum is a critical sensorimotor structure that exhibits protracted postnatal development
in mammals. Many aspects of cerebellar circuit development are activity dependent, …

Early neural activity in the developing sensory system comprises spontaneous bursts of
patterned activity, which is fundamental for sculpting and refinement of immature cortical …

Sensory deprivation from the periphery impacts cortical development. Otoferlin deficiency
leads to impaired cochlear synaptic transmission and is associated with progressive hearing …

Sensory perturbation in one modality results in the adaptive reorganization of neural pathways
within the spared modalities, a phenomenon known as “crossmodal plasticity,” which has …

10.7554/eLife.38213.001 In week-old rats, somatosensory input arises predominantly from
external stimuli or from sensory feedback (reafference) associated with myoclonic twitches …

In the developing visual system before eye opening, spontaneous retinal waves trigger bursts
of neural activity in downstream structures, including visual cortex. At the same ages when …

The role of the medial septum in suppressing paradoxical sleep and promoting slow wave
sleep was suggested on the basis of neurotoxic lesion studies. However, these conclusions …

The cortex is composed of neuronal types with diverse gene expression that are organized
into specialized cortical areas. These areas, each with characteristic cytoarchitecture ( …

BACKGROUND: Fibromyalgia (FM) is associated with widespread autonomic dysfunction
where sympathetic predominance explains associated complaints such as widespread pain, …