[PDF][PDF] Wnt antagonists bind through a short peptide to the first β-propeller domain of LRP5/6

…, W Wang, C Tam, J Hwang, Y Zhang, D Spittler… - Structure, 2011 - cell.com
The Wnt pathway inhibitors DKK1 and sclerostin (SOST) are important therapeutic targets in
diseases involving bone loss or damage. It has been appreciated that Wnt coreceptors LRP5…

[HTML][HTML] Selective BET bromodomain inhibition as an antifungal therapeutic strategy

…, D Maubon, Y Zhou, M Harbut, D Spittler… - Nature …, 2017 - nature.com
Invasive fungal infections cause significant morbidity and mortality among immunocompromised
individuals, posing an urgent need for new antifungal therapeutic strategies. Here we …

Binding stoichiometry and structural model of the HIV-1 Rev/Importin β complex

D Spittler, RL Indorato, EB Erba… - Life Science …, 2022 - life-science-alliance.org
HIV-1 Rev mediates the nuclear export of intron-containing viral RNA transcripts and is
essential for viral replication. Rev is imported into the nucleus by the host protein importin β (Impβ…

[HTML][HTML] Freins et leviers de la prise en charge du traitement post-exposition au VIH

…, X Mabire 2, S Roduit 1, V Laguette 2, D Spittler 1… - Santé publique, 2016 - cairn.info
Introduction : Dans un contexte d’émergence de la prévention combinée du VIH en France,
le traitement post-exposition (TPE) apparaît mal connu et sous-utilisé. Cette étude vise à …

Barriers and levers to HIV post-exposure prophylaxis

…, X Mabire, S Roduit, V Laguette, D Spittler… - Sante Publique, 2016 - cairn-int.info
Introduction: In the context of emerging combined prevention of HIV in France, post-exposure
prophylaxis (PEP) appears to be poorly known and underutilized. This study was designed …

Unimagined Community. Sex, Networks, and AIDS in Uganda and South Africa

TO Beidelman - 2009 - JSTOR
Spittler' s argument about the marginality of the anthropology … The intellectual continuities
shown so convincingly by Spittler… many others not mentioned by Spittler, yet his argument is on …

The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders

A Andrieux, PA Salin, M Vernet, P Kujala… - Genes & …, 2002 - genesdev.cshlp.org
Neurons contain abundant subsets of highly stable microtubules that resist depolymerizing
conditions such as exposure to the cold. Stable microtubules are thought to be essential for …

[PDF][PDF] The moral dimension of economy: work, workfare, and fairness in provincial Hungary

C Hann - 2016 - pure.mpg.de
Didier Fassin distances himself from any form of reification when he notes that “moral
economies are unstable or at least fluid realities traversed by tensions and contradictions, since …

Assessment of the impact of oxidation processes on indoor air pollution using the new time-resolved INCA-Indoor model

M Mendez, N Blond, P Blondeau… - Atmospheric …, 2015 - Elsevier
INCA-Indoor, a new indoor air quality (IAQ) model, has been developed to simulate the
concentrations of volatile organic compounds (VOC) and oxidants considering indoor air specific …

Moral (ity and) economy: Work, workfare, and fairness in provincial Hungary

C Hann - European Journal of Sociology/Archives Européennes …, 2018 - cambridge.org
Didier Fassin protects himself against such a charge when he notes that “moral economies
are unstable or at least fluid realities traversed by tensions and contradictions, since conflicts …