User profiles for Didong Li
Didong LiAssistant Professor, Department of Biostatistics, Gillings School of Global Public Health … Verified email at unc.edu Cited by 239 |
[HTML][HTML] Alignment of spatial genomics data using deep Gaussian processes
Spatially resolved genomic technologies have allowed us to study the physical organization
of cells and tissues, and promise an understanding of local interactions between cells. …
of cells and tissues, and promise an understanding of local interactions between cells. …
Estimating densities with non-linear support by using Fisher–Gaussian kernels
M Mukhopadhyay, D Li… - Journal of the Royal …, 2020 - academic.oup.com
Current tools for multivariate density estimation struggle when the density is concentrated
near a non-linear subspace or manifold. Most approaches require the choice of a kernel, with …
near a non-linear subspace or manifold. Most approaches require the choice of a kernel, with …
Probabilistic contrastive principal component analysis
D Li, A Jones, B Engelhardt - arXiv preprint arXiv:2012.07977, 2020 - arxiv.org
Dimension reduction is useful for exploratory data analysis. In many applications, it is of
interest to discover variation that is enriched in a "foreground" dataset relative to a "background" …
interest to discover variation that is enriched in a "foreground" dataset relative to a "background" …
Alignment of spatial genomics and histology data using deep Gaussian processes
Spatially-resolved genomic technologies have allowed us to study the physical organization
of cells and tissues, and promise an understanding of the local interactions between cells. …
of cells and tissues, and promise an understanding of the local interactions between cells. …
[PDF][PDF] Geodesic distance estimation with spherelets
Many statistical and machine learning approaches rely on pairwise distances between data
points. The choice of distance metric has a fundamental impact on performance of these …
points. The choice of distance metric has a fundamental impact on performance of these …
[HTML][HTML] 2D Dubins path in environments with obstacle
D Yang, D Li, H Sun - Mathematical Problems in Engineering, 2013 - hindawi.com
We recapitulate the achievement about the Dubins path as well as some precise proofs which
are important but omitted by Dubins. Then we prove that the shortest path ( -geodesic) in …
are important but omitted by Dubins. Then we prove that the shortest path ( -geodesic) in …
Contrastive latent variable modeling with application to case-control sequencing experiments
… Some covariance inequality tests have attempted to address the problem of highdimensional
data by using estimators of the distance between covariance matrices based on the …
data by using estimators of the distance between covariance matrices based on the …
Efficient manifold approximation with spherelets
D Li, M Mukhopadhyay… - Journal of the Royal …, 2022 - academic.oup.com
In statistical dimensionality reduction, it is common to rely on the assumption that high
dimensional data tend to concentrate near a lower dimensional manifold. There is a rich literature …
dimensional data tend to concentrate near a lower dimensional manifold. There is a rich literature …
Inference for Gaussian processes with Matérn covariogram on compact Riemannian manifolds
Gaussian processes are widely employed as versatile modelling and predictive tools in
spatial statistics, functional data analysis, computer modelling and diverse applications of …
spatial statistics, functional data analysis, computer modelling and diverse applications of …
[HTML][HTML] Absolute Winding Number Differentiates Mouse Spatial Navigation Strategies With Genetic Risk for Alzheimer's Disease
Spatial navigation and orientation are emerging as promising markers for altered cognition
in prodromal Alzheimer’s disease, and even in cognitively normal individuals at risk for …
in prodromal Alzheimer’s disease, and even in cognitively normal individuals at risk for …