Salinity represents a critical environmental factor for all aquatic organisms, including fishes.
Environments of stable salinity are inhabited by stenohaline fishes having narrow salinity …

In their aqueous habitats, fish are exposed to a wide range of osmotic conditions and differ
in their abilities to respond adaptively to these variations in salinity. Fish species that inhabit …

▪ Abstract The cellular stress response is a universal mechanism of extraordinary
physiological/pathophysiological significance. It represents a defense reaction of cells to damage …

We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200
megabases and contains at least 30,907 genes. The high gene count is a consequence of an …

Background Concerns have been raised about the biological and toxicologic effects of the
antimicrobials triclocarban (TCC) and triclosan (TCS) in personal care products. Few studies …

Cells respond to acute environmental change by activating a stress response that is widely
studied. However, knowledge of this stress response is fragmentary, and a unifying concept …

▪ Abstract Adaptation of cells to hypertonicity often involves changes in gene expression.
Since the concentration of salt in the interstitial fluid surrounding renal inner medullary cells …

Background Renal cell carcinoma (RCC) is the sixth leading cause of cancer death and is
responsible for 11,000 deaths per year in the US. Approximately one-third of patients present …

This study demonstrates, by using neutral comet assay and pulsed field gel electrophoresis,
that hyperosmotic stress causes DNA damage in the form of double strand breaks (dsb). …

Cells respond to changes in osmotic pressure with compensatory molecular adaptations
that allow them to re-establish homeostasis of osmotically disturbed aspects of cell structure …