Notch signalling restricts inflammation and serpine1 expression in the dynamic endocardium of the regenerating zebrafish heart

J Münch, D Grivas, Á González-Rajal… - …, 2017 - journals.biologists.com
The zebrafish heart regenerates after ventricular damage through a process involving
inflammation, fibrotic tissue deposition/removal and myocardial regeneration. Using 3D whole-…

[HTML][HTML] NOTCH pathway inactivation promotes bladder cancer progression

…, JL Martinez-Torrecuadrada, D Grivas… - The Journal of …, 2015 - Am Soc Clin Investig
NOTCH signaling suppresses tumor growth and proliferation in several types of stratified
epithelia. Here, we show that missense mutations in NOTCH1 and NOTCH2 found in human …

Method for estimating transition probability in bridge deterioration models

PD DeStefano, DA Grivas - Journal of infrastructure systems, 1998 - ascelibrary.org
A method for estimating transition probability is applied to the deterioration models of a
bridge management system. Deterioration is modeled as a time-dependent function of the …

Cooperative Response to Endocardial Notch Reveals Interaction With Hippo Pathway

L Luna-Zurita, BG Flores-Garza, D Grivas… - Circulation …, 2023 - Am Heart Assoc
BACKGROUND: The endocardium is a crucial signaling center for cardiac valve development
and maturation. Genetic analysis has identified several human endocardial genes whose …

[HTML][HTML] Loss of Caveolin-1 and caveolae leads to increased cardiac cell stiffness and functional decline of the adult zebrafish heart

D Grivas, Á González-Rajal, C Guerrero Rodríguez… - Scientific reports, 2020 - nature.com
Caveolin-1 is the main structural protein of caveolae, small membrane invaginations involved
in signal transduction and mechanoprotection. Here, we generated cav1-KO zebrafish …

State increment optimization methodology for network-level pavement management

DA Grivas, V Ravirala, BC Schultz - Transportation research record, 1993 - trid.trb.org
An optimization methodology is presented for program planning and budget allocation
involved in network-level pavement management. It consists of three major components:(a) …

Network-level pavement performance prediction model incorporating censored data

RR DeLisle, P Sullo, DA Grivas - Transportation research …, 2003 - journals.sagepub.com
A methodology is presented for network-level pavement performance prediction that incorporates
censored condition data. Censoring occurs when the duration at a specific condition …

[HTML][HTML] Midkine-a regulates the formation of a fibrotic scar during zebrafish heart regeneration

D Grivas, Á González-Rajal… - Frontiers in Cell and …, 2021 - frontiersin.org
Unlike the hearts of mammals, the adult zebrafish heart regenerates after injury. Heart
cryoinjury in zebrafish triggers the formation of a fibrotic scar that gradually degrades, leading to …

State increment method of life-cycle cost analysis for highway management

V Ravirala, DA Grivas - Journal of Infrastructure Systems, 1995 - ascelibrary.org
A state increment method of life-cycle cost analysis (SILCCA) is presented for project-level
evaluation of highway infrastructure maintenance options. The method involves: (1) …

How accurate is ground-penetrating radar for bridge deck condition assessment?

H Shin, DA Grivas - Transportation research record, 2003 - journals.sagepub.com
As ground-penetrating radar (GPR) is increasingly used for assessing the condition of bridge
decks, quantifying and controlling the quality of GPR measures becomes an important …