User profiles for Dimos Goundaroulis

Dimos Goundaroulis

Lecturer, Baylor College of Medicine
Verified email at bcm.edu
Cited by 513

KnotProt 2.0: a database of proteins with knots and other entangled structures

…, P Rubach, D Goundaroulis… - Nucleic acids …, 2019 - academic.oup.com
The KnotProt 2.0 database (the updated version of the KnotProt database) collects information
about proteins which form knots and other entangled structures. New features in KnotProt …

[HTML][HTML] Topological models for open-knotted protein chains using the concepts of knotoids and bonded knotoids

D Goundaroulis, N Gügümcü, S Lambropoulou… - Polymers, 2017 - mdpi.com
In this paper we introduce a method that offers a detailed overview of the entanglement of
an open protein chain. Further, we present a purely topological model for classifying open …

[HTML][HTML] Studies of global and local entanglements of individual protein chains using the concept of knotoids

D Goundaroulis, J Dorier, F Benedetti, A Stasiak - Scientific reports, 2017 - nature.com
We study here global and local entanglements of open protein chains by implementing the
concept of knotoids. Knotoids have been introduced in 2012 by Vladimir Turaev as a …

Knoto-ID: a tool to study the entanglement of open protein chains using the concept of knotoids

J Dorier, D Goundaroulis, F Benedetti, A Stasiak - Bioinformatics, 2018 - academic.oup.com
The backbone of most proteins forms an open curve. To study their entanglement, a
common strategy consists in searching for the presence of knots in their backbones using …

[HTML][HTML] Chromatin loop extrusion and chromatin unknotting

D Racko, F Benedetti, D Goundaroulis, A Stasiak - Polymers, 2018 - mdpi.com
It has been a puzzle how decondensed interphase chromosomes remain essentially unknotted.
The natural expectation is that in the presence of type II DNA topoisomerases that permit …

[PDF][PDF] Chromatin is frequently unknotted at the megabase scale

D Goundaroulis, EL Aiden, A Stasiak - Biophysical journal, 2020 - cell.com
Knots in the human genome would greatly impact diverse cellular processes ranging from
transcription to gene regulation. To date, it has not been possible to directly examine the …

A systematic classification of knotoids on the plane and on the sphere

D Goundaroulis, J Dorier, A Stasiak - arXiv preprint arXiv:1902.07277, 2019 - arxiv.org
DIMOS GOUNDAROULIS, JULIEN DORIER, AND ANDRZEJ STASIAK … DIMOS
GOUNDAROULIS, JULIEN DORIER, AND ANDRZEJ STASIAK … DIMOS GOUNDAROULIS …

-curves in proteins

P Dabrowski-Tumanski, D Goundaroulis… - arXiv preprint arXiv …, 2019 - arxiv.org
Apart from the knots formed by the main-chain, the proteins can form numerous topological
structures, when included the covalent and ion-mediated interactions. In this work, we define …

Framization of the Temperley-Lieb algebra

D Goundaroulis, J Juyumaya, A Kontogeorgis… - arXiv preprint arXiv …, 2013 - arxiv.org
We propose a framization of the Temperley-Lieb algebra. The framization is a procedure that
can briefly be described as the adding of framing to a known knot algebra in a way that is …

The Yokonuma-Temperley-Lieb Algebra

D Goundaroulis, J Juyumaya, A Kontogeorgis… - arXiv preprint arXiv …, 2010 - arxiv.org
In this paper we introduce the Yokonuma-Temperley-Lieb algebra as a quotient of the
Yokonuma-Hecke algebra over a two-sided ideal generated by an expression analogous to the …