From a technical point of view a flow cytometer is a light detection device capable of detecting
photons of different wavelengths over a high dynamic range. In order to achieve a high …

Mesenchymal responses are an essential aspect of tissue repair. Failure to terminate this
repair process correctly, however, results in fibrosis and organ dysfunction. Therapies that …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Hepatic insulin resistance is a driving force in the pathogenesis of type 2 diabetes mellitus (T2DM)
and is tightly coupled with excessive storage of fat and the ensuing inflammation …

The critical size for strong interaction of hydrophobic particles with phospholipid bilayers
has been predicted to be 10 nm. Because of the wide spreading of nonpolar nanoparticles (NPs…

Cell-to-cell propagation of aggregated alpha synuclein (aSyn) has been suggested to play
an important role in the progression of alpha synucleinopathies. A critical step for the …

We provide a robust four-color fluorescence-based flow cytometry protocol that distinguishes
viable dividing plasmablasts from nondividing plasma cells and, based on CD19 surface …

Blood coagulation is essential for physiological hemostasis but simultaneously contributes
to thrombotic disease. However, molecular and cellular events controlling initiation and …

In many societies, the majority of adults regularly consume alcohol. However, only a small
proportion develops alcohol addiction. Individuals at risk often show a high sensation-seeking/…

To elucidate the function of oxidative phosphorylation (OxPhos) during B cell differentiation,
we employ CD23Cre-driven expression of the dominant-negative K320E mutant of the …