[HTML][HTML] CD44highCD24low molecular signature determines the cancer stem cell and EMT phenotype in oral squamous cell carcinoma
S Ghuwalewala, D Ghatak, P Das, S Dey, S Sarkar… - Stem cell …, 2016 - Elsevier
Almost all epithelial tumours contain cancer stem-like cells, which possess a unique property
of self-renewal and differentiation. In oral cancer, several biomarkers including cell surface …
of self-renewal and differentiation. In oral cancer, several biomarkers including cell surface …
[HTML][HTML] Cancer stemness: p53 at the wheel
D Ghatak, D Das Ghosh, S Roychoudhury - Frontiers in oncology, 2021 - frontiersin.org
The tumor suppressor p53 maintains an equilibrium between self-renewal and differentiation
to sustain a limited repertoire of stem cells for proper development and maintenance of …
to sustain a limited repertoire of stem cells for proper development and maintenance of …
[HTML][HTML] MiRNA-146a/AKT/β-catenin activation regulates cancer stem cell phenotype in oral squamous cell carcinoma by targeting CD24
CD44 high CD24 low population has been previously reported as cancer stem cells (CSCs)
in Oral Squamous Cell Carcinoma (OSCC). Increasing evidence suggests potential …
in Oral Squamous Cell Carcinoma (OSCC). Increasing evidence suggests potential …
p53 gain‐of‐function mutations increase Cdc7‐dependent replication initiation
Cancer‐associated p53 missense mutants confer gain of function ( GOF ) and promote
tumorigenesis by regulating crucial signaling pathways. However, the role of GOF mutant p53 in …
tumorigenesis by regulating crucial signaling pathways. However, the role of GOF mutant p53 in …
[HTML][HTML] Transcriptional control of mitosis: deregulation and cancer
Research over the past few decades has well established the molecular functioning of mitosis.
Deregulation of these functions has also been attributed to the generation of aneuploidy …
Deregulation of these functions has also been attributed to the generation of aneuploidy …
MicroRNA-324-5p–CUEDC2 Axis Mediates Gain-of-Function Mutant p53-Driven Cancer Stemness
D Ghatak, A Datta, T Roychowdhury… - Molecular Cancer …, 2021 - AACR
… Dishari Ghatak; Dishari Ghatak … Ghatak and A. Datta contributed equally as co-authors
of this article. …
of this article. …
[HTML][HTML] Genome-wide small RNA sequencing identifies micrornas deregulated in non-small cell lung carcinoma harboring gain-of-function mutant P53
Mutations in the TP53 gene are one of the most frequent events in cancers. Certain missense
mutant p53 proteins gain oncogenic functions (gain-of-functions) and drive tumorigenesis. …
mutant p53 proteins gain oncogenic functions (gain-of-functions) and drive tumorigenesis. …
MiR-146a-dependent regulation of CD24/AKT/β-catenin axis drives cancer stem cell phenotype in oral squamous cell carcinoma
Cancer stem cells (CSCs) are known to potentiate tumor initiation and maintenance in Oral
Squamous Cell Carcinoma (OSCC). Increasing evidences suggest that CD44 high CD24 low …
Squamous Cell Carcinoma (OSCC). Increasing evidences suggest that CD44 high CD24 low …
[CITATION][C] Studies on the gain of function mutant p53 mediated cancer cell stemness
D Ghatak - shodhganga.inflibnet.ac.in
Shodhganga@INFLIBNET: Studies on the gain of function mutant p53 mediated cancer cell
stemness Skip navigation DSpace logo Home Browse Universities & Departments Browse by …
stemness Skip navigation DSpace logo Home Browse Universities & Departments Browse by …