User profiles for Dmitrii Y. Travin
 | Dmitrii TravinPostdoctoral Research Associate, University of Illinois Chicago Verified email at uic.edu Cited by 267 |
[HTML][HTML] Structure of ribosome-bound azole-modified peptide phazolicin rationalizes its species-specific mode of bacterial translation inhibition
DY Travin, ZL Watson, M Metelev, FR Ward… - Nature …, 2019 - nature.com
Ribosome-synthesized post-translationally modified peptides (RiPPs) represent a rapidly
expanding class of natural products with various biological activities. Linear azol(in)e-…
expanding class of natural products with various biological activities. Linear azol(in)e-…
[PDF][PDF] Architecture of microcin B17 synthetase: an octameric protein complex converting a ribosomally synthesized peptide into a DNA gyrase poison
The introduction of azole heterocycles into a peptide backbone is the principal step in the
biosynthesis of numerous compounds with therapeutic potential. One of them is microcin B17, …
biosynthesis of numerous compounds with therapeutic potential. One of them is microcin B17, …
[HTML][HTML] Natural Trojan horse inhibitors of aminoacyl-tRNA synthetases
DY Travin, K Severinov, S Dubiley - RSC Chemical Biology, 2021 - pubs.rsc.org
… Dmitrii Y. Travin received his MSc degree in bioengineering and bioinformatics from …
Dmitrii performs genome mining and characterization of novel azole-containing peptides …
Dmitrii performs genome mining and characterization of novel azole-containing peptides …
Dual-uptake mode of the antibiotic phazolicin prevents resistance acquisition by gram-negative bacteria
DY Travin, R Jouan, A Vigouroux, S Inaba-Inoue… - MBio, 2023 - Am Soc Microbiol
Phazolicin (PHZ) is a peptide antibiotic exhibiting narrow-spectrum activity against rhizobia
closely related to its producer, Rhizobium sp. strain Pop5. Here, we show that the frequency …
closely related to its producer, Rhizobium sp. strain Pop5. Here, we show that the frequency …
Biosynthesis of translation inhibitor klebsazolicin proceeds through heterocyclization and N-terminal amidine formation catalyzed by a single YcaO enzyme
DY Travin, M Metelev, M Serebryakova… - Journal of the …, 2018 - ACS Publications
Klebsazolicin (KLB) is a recently discovered Klebsiella pneumonia peptide antibiotic targeting
the exit tunnel of bacterial ribosome. KLB contains an N-terminal amidine ring and four …
the exit tunnel of bacterial ribosome. KLB contains an N-terminal amidine ring and four …
[HTML][HTML] Translation-targeting RiPPs and where to find them
DY Travin, D Bikmetov, K Severinov - Frontiers in Genetics, 2020 - frontiersin.org
Prokaryotic translation is among the major targets of diverse natural products with antibacterial
activity including several classes of clinically relevant antibiotics. In this review, we …
activity including several classes of clinically relevant antibiotics. In this review, we …
Complete Genome Sequences of Two Rhizobium Strains Producing Azol(in)e-Modified Antibiotics
Rhizobia are known for their ability to establish symbiotic relationships with plants. The
specialized metabolism of these bacteria remains understudied. Here, we report whole-genome …
specialized metabolism of these bacteria remains understudied. Here, we report whole-genome …
The antibiotic phazolicin displays a dual mode of uptake in Gram-negative bacteria
DY Travin, A Vigouroux, S Inaba-Inoue, F Qu, R Jouan… - bioRxiv, 2022 - biorxiv.org
Phazolicin (PHZ) is a peptide antibiotic exhibiting narrow-spectrum activity against rhizobia
closely related to its producer Rhizobium sp. Pop5. Using genetic and biochemical …
closely related to its producer Rhizobium sp. Pop5. Using genetic and biochemical …
Phazolicin–a Novel Thiazole/Oxazole-Modified Peptide Inhibiting the Bacterial Ribosome in a Species-Specific Way
DY Travin, ZL Watson, M Metelev, FR Ward… - bioRxiv, 2019 - biorxiv.org
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a rapidly
expanding and largely untapped class of natural products with various biological activities. …
expanding and largely untapped class of natural products with various biological activities. …
[CITATION][C] Abstract P-19: Cryo-EM Structure of a New Thiazole/Oxazole-Modified Microcin-Phasolicin-in Complex with Bacterial Ribosome Provides Basis for …
DY Travin, Z Watson, M Metelev, F Ward… - International Journal of …, 2019 - elibrary.ru
ABSTRACT P-19: CRYO-EM STRUCTURE OF A NEW THIAZOLE/OXAZOLE-MODIFIED
MICROCIN-PHASOLICIN-IN COMPLEX WITH BACTERIAL RIBOSOME PROVIDES BASIS …
MICROCIN-PHASOLICIN-IN COMPLEX WITH BACTERIAL RIBOSOME PROVIDES BASIS …