Inducing organogenesis in 3D culture is an important aspect of stem cell research. Anterior
neural structures have been produced from large embryonic stem cell (ESC) aggregates, but …

Three-dimensional organoid constructs serve as increasingly widespread in vitro models for
development and disease modeling. Current approaches to recreate morphogenetic …

Purpose.: Retinal degeneration initiated by loss of photoreceptors is the prevalent cause of
visual impairment and blindness in industrialized countries. Transplantation of photoreceptor …

Transplantation of photoreceptor precursor cells (PPCs) into the retina represents a promising
treatment for cell replacement in blinding diseases characterized by photoreceptor loss. In …

Vision impairment and blindness due to the loss of the light-sensing cells of the retina, ie
photoreceptors, represents the main reason for disability in industrialized countries. …

Correlative microscopy combines the versatility of the light microscope with the excellent
spatial resolution of the electron microscope. Here, we describe fast and simple methods for …

Abstract Changes in axonal myelination are an important hallmark of aging and a number of
neurological diseases. Demyelinated axons are impaired in their function and degenerate …

The alteration or decrease of axonal myelination is an important hallmark of aging and
disease. Demyelinated axons are impaired in their function and degenerate over time. …

abstract Changes in axonal myelination are an important hallmark of aging and a number of
neurological diseases. Demyelinated axons are impaired in their function and degenerate …

Purpose:: Prominin-1 (PROM1, AC133, CD133, PROML1) is a 5-transmembrane-domain
glycoprotein located at plasma membrane protrusions and expressed in various tissues. To …