ATP-binding cassette (ABC) transporter proteins carry diverse substrates across cell
membranes 1 . Whereas clinically relevant ABC exporters are implicated in various diseases or …

The application of fluorescence microscopy in cell biology often generates a huge amount
of imaging data. Automated whole cell segmentation of such data enables the detection and …

The enhanced permeability and retention (EPR) effect is the only described mechanism
enabling nanoparticles (NPs) flowing in blood to reach tumors by a passive targeting mechanism…

Cathelicidin antimicrobial peptides are multifunctional peptides that are important in the innate
immune system of mammals. Cathelicidins have been identified in several fish species. In …

Cobalamin (Cbl; vitamin B 12 ) is an essential micronutrient synthesized only by bacteria.
Mammals have developed a sophisticated uptake system to capture the vitamin from the diet. …

The invariant chain (Ii, also known as CD74) is a multifunctional regulator of adaptive
immune responses and is responsible for sorting major histocompatibility complex class I and …

Rab5 and Rab7a are the main determinants of early and late endosomes and are important
regulators of endosomal progression. The transport from early endosomes to late endosome …

Contact-dependent intercellular transfer (codeIT) of cellular constituents can have functional
consequences for recipient cells, such as enhanced survival and drug resistance. …

Invariant chain (Ii) is an important multifunctional player in the regulation of adaptive immune
responses and is responsible for several cellular functions related to MHCI and MHCII …

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