Histopathological diagnosis of biopsy samples and margin assessment of surgical
specimens are challenging aspects in sarcoma. Using dog patient tissues, we assessed the …

Rapid, sensitive, precise and accurate analysis of samples in their native in vivo
environment is critical to better decipher physiological and physiopathological mechanisms. …

TG6002 is an oncolytic vaccinia virus expressing FCU1 protein, which converts 5-fluorocytosine
into 5-fluorouracil. The study objectives were to assess tolerance, viral replication, 5-…

Purpose: F14512 is a new topoisomerase II inhibitor containing a spermine moiety that
facilitates selective uptake by tumor cells and increases topoisomerase II poisoning. F14512 is …

Background Formalin-fixed paraffin-embedded (FFPE) tissue has been the gold standard
for routine pathology for general and cancer postoperative diagnostics. Despite robust …

Immunization with xenogeneic DNA is a promising cancer treatment to overcome tolerance
to self-antigens. Heat shock protein 70 (HSP70) is over-expressed in various kinds of tumors …

Purpose The purpose of this study was to assess the feasibility and efficacy of docetaxel-loaded
bead chemoembolization in spontaneous prostate cancer in a canine model. Materials …

Here, we present an approach to identify N-linked glycoproteins and deduce their spatial
localization using a combination of matrix-assisted laser desorption ionization (MALDI) N-…

Background Cancer heterogeneity is a main obstacle for the development of effective therapies,
as its replication in in vitro preclinical models is challenging. Around 96% of developed …

Background Metastatic melanoma is one of the most aggressive forms of cancer in humans.
Among its types, mucosal melanomas represent one of the most highly metastatic and …