[PDF][PDF] Host cell traversal is important for progression of the malaria parasite through the dermis to the liver

R Amino, D Giovannini, S Thiberge, P Gueirard… - Cell host & …, 2008 - cell.com
The malaria sporozoite, the parasite stage transmitted by the mosquito, is delivered into the
dermis and differentiates in the liver. Motile sporozoites can invade host cells by disrupting …

Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export

A Legati, D Giovannini, G Nicolas, U López-Sánchez… - Nature …, 2015 - nature.com
Primary familial brain calcification (PFBC) is a neurological disease characterized by calcium
phosphate deposits in the basal ganglia and other brain regions and has thus far been …

[PDF][PDF] Inorganic phosphate export by the retrovirus receptor XPR1 in metazoans

D Giovannini, J Touhami, P Charnet, M Sitbon… - Cell reports, 2013 - cell.com
Inorganic phosphate uptake is a universal function accomplished by transporters that are
present across the living world. In contrast, no phosphate exporter has ever been identified in …

[HTML][HTML] Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs

…, Y Rouillé, M Tauziet, D Giovannini… - Nature …, 2022 - nature.com
CRISPR knockout (KO) screens have identified host factors regulating severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) replication. Here, we conducted a meta-analysis …

[PDF][PDF] Independent roles of apical membrane antigen 1 and rhoptry neck proteins during host cell invasion by apicomplexa

D Giovannini, S Späth, C Lacroix, A Perazzi… - Cell host & …, 2011 - cell.com
During invasion, apicomplexan parasites form an intimate circumferential contact with the
host cell, the tight junction (TJ), through which they actively glide. The TJ, which links the …

[PDF][PDF] Clonal conditional mutagenesis in malaria parasites

A Combe, D Giovannini, TG Carvalho, S Spath… - Cell host & …, 2009 - cell.com
We describe here an efficient method for conditional gene inactivation in malaria parasites
that uses the Flp/FRT site-specific recombination system of yeast. The method, developed in …

FLP/FRT-mediated conditional mutagenesis in pre-erythrocytic stages of Plasmodium berghei

C Lacroix, D Giovannini, A Combe, DY Bargieri… - Nature protocols, 2011 - nature.com
We describe here a highly efficient procedure for conditional mutagenesis in Plasmodium.
The procedure uses the site-specific recombination FLP-FRT system of yeast and targets the …

XPR1 mutations are a rare cause of primary familial brain calcification

M Anheim, U López-Sánchez, D Giovannini… - Journal of …, 2016 - Springer
Mutations in XPR1, a gene encoding an inorganic phosphate exporter, have recently been
identified in patients with primary familial brain calcification (PFBC). Using Sanger …

Documentation and analysis of children's experience: An ongoing collegial activity for early childhood professionals

M Picchio, D Giovannini, S Mayer, T Musatti - Early Years, 2012 - Taylor & Francis
Systematic documentation and analysis of educational practice can be a powerful tool for
continuous support to the professionalism of early childhood education practitioners. This …

Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal coronaviruses

…, Y Rouillé, M Tauziet, M Arnaud-Arnould, D Giovannini… - bioRxiv, 2021 - biorxiv.org
Several genome-wide CRISPR knockout screens have been conducted to identify host
factors regulating SARS-CoV-2 replication, but the models used have often relied on …