Stressful life events are major environmental risk factors for anxiety disorders, although not
all individuals exposed to stress develop clinical anxiety. The molecular mechanisms …

Selective Serotonin Reuptake Inhibitors (SSRIs) are commonly used drugs for the treatment
of psychiatric diseases including major depressive disorder (MDD). For unknown reasons a …

Peripheral nerve injury can induce pathological conditions that lead to persistent sensitized
nociception. Although there is evidence that plastic changes in the cortex contribute to this …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by amyloid beta (Aβ)
deposits, hyperphosphorylated tau deposition, and cognitive dysfunction. Abnormalities in …

Recent interest in the role of microbiota in health and disease has implicated gut microbiota
dysbiosis in psychiatric disorders including major depressive disorder. Several …

While N-linked glycosylation has been extensively studied in the context of inflammatory
and metabolic disorders, its relationship with major depressive disorder (MDD) and …

Selective serotonin reuptake inhibitors (SSRIs) are the predominant drugs prescribed for
Major Depressive Disorder. The immediate pharmacological target of SSRIs is the serotonin …

Cytosine arabinoside (AraC) is one of the main therapeutic treatments for several types of
cancer, including acute myeloid leukaemia. However, after a high-dose AraC chemotherapy …

To identify common genetic variants that contribute to lung cancer susceptibility, we conducted
a multistage genome-wide association study of lung cancer in Asian women who never …

Fluoxetine is an antidepressant commonly prescribed not only to adults but also to children
for the treatment of depression, obsessive-compulsive disorder, and neurodevelopmental …