Temporal lobe epilepsy is a common, chronic neurological disorder characterized by recurrent
spontaneous seizures. MicroRNAs (miRNAs) are small, noncoding RNAs that regulate …

Background Candida infection of the central nervous system (CNS) following neurosurgery
is relatively unusual but is associated with significant morbidity and mortality. We present our …

Object The authors analyzed the role of endoscopic third ventriculostomy (ETV) as a primary
treatment for hydrocephalus and also as an alternative to shunt revision for malfunctioning …

Neuroinflammation is thought to contribute to the pathogenesis and maintenance of temporal
lobe epilepsy, but the underlying cell and molecular mechanisms are not fully understood. …

Synaptic downscaling is a homeostatic mechanism that allows neurons to reduce firing rates
during chronically elevated network activity. Although synaptic downscaling is important in …

There is a need for diagnostic biomarkers of epilepsy and status epilepticus to support clinical
examination, electroencephalography and neuroimaging. Extracellular microRNAs may …

Object The primary aim of this study was to evaluate the success of endoscopic third
ventriculostomy (ETV) as a treatment for obstructive hydrocephalus secondary to midline tumors (…

Current anti-epileptic drugs (AEDs) act on a limited set of neuronal targets, are ineffective in
a third of patients with epilepsy, and do not show disease-modifying properties. MicroRNAs …

Introduction The indications for surgical repair of congenital brachial plexus palsy are
controversial. Our objective was to determine the results of early brachial plexus surgery following …

Transfer RNAs (tRNAs) are a major class of noncoding RNA. Stress-induced cleavage of
tRNA is highly conserved and results in tRNA fragments. Here, we found that specific tRNA …