Background: An elevated plasma homocysteine concentration is a putative risk factor for
cardiovascular disease. Observational studies have reported an association between coffee …

Prostate cancer is the most prevalent noncutaneous cancer in males in developed regions
1 , with African American men having among the highest worldwide incidence and mortality …

We identified DD3 PCA3 as one of the most prostate cancer-specific genes at present (MJ
Bussemakers et al. Cancer Res., 59: 5975–5979, 1999). Consequently, DD3 PCA3 is an …

We performed a genome-wide association scan to search for sequence variants conferring
risk of prostate cancer using 1,501 Icelandic men with prostate cancer and 11,290 controls. …

Iron deficiency is one of the leading contributors to the global burden of disease, and
particularly affects children, premenopausal women, and people in low-income and middle-income …

For interpretation of quantitative gene expression measurements in clinical tumor samples,
a normalizer is necessary to correct expression data for differences in cellular input, RNA …

Familial clustering studies indicate that breast cancer risk has a substantial genetic
component 1 , 2 , 3 . To identify new breast cancer risk variants, we genotyped approximately …

Adult human height is one of the classical complex human traits 1 . We searched for sequence
variants that affect height by scanning the genomes of 25,174 Icelanders, 2,876 Dutch, …

Background: We present a large European population-based study of thyroid function,
performed in a population with longstanding borderline sufficient iodine intake. Methods: The …

Background In-home iron fortification for infants in developing countries is recommended for
control of anaemia, but low absorption typically results in >80% of the iron passing into the …