Emerging strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
causative agent of the coronavirus disease 2019 (COVID-19) pandemic, that show increased …

The global vaccination programme against smallpox led to its successful eradication and
averted millions of deaths. Monkeypox virus (MPXV) is a close relative of the Variola (smallpox) …

Interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) can restrict viral pathogens,
but pro- and anti-viral activities have been reported for coronaviruses. Here, we show that …

Recent evidence shows that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
is sensitive to interferons (IFNs). However, the most effective types of IFNs and the …

The cellular factor serine incorporator 5 (SERINC5) impairs HIV-1 infectivity but is antagonized
by the viral Nef protein. We analyzed the anti-SERINC5 activity of Nef proteins across …

It has recently been shown that an early SARS-CoV-2 isolate (NL-02-2020) hijacks
interferon-induced transmembrane proteins (IFITMs) for efficient replication in human lung cells, …

CpG dinucleotide suppression has been reported to allow HIV-1 to evade inhibition by the
zinc-finger antiviral protein (ZAP). Here, we show that primate lentiviruses display marked …

The zinc finger antiviral protein (ZAP) is a broad inhibitor of virus replication. Its best-characterized
function is to bind CpG dinucleotides present in viral RNAs and, through the …

Opposing effects of interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) on SARS-CoV-2
infection have been reported. The reasons for this are unclear and the role of IFITMs …

Human immunodeficiency virus type 1 (HIV-1) groups M, N, O, and P are the result of
independent zoonotic transmissions of simian immunodeficiency viruses (SIVs) infecting great …