DNA mismatch repair

TA Kunkel, DA Erie - Annu. Rev. Biochem., 2005 - annualreviews.org
▪ Abstract DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects
mismatches generated during DNA replication and escape proofreading. MMR proteins also …

Eukaryotic mismatch repair in relation to DNA replication

TA Kunkel, DA Erie - Annual review of genetics, 2015 - annualreviews.org
Three processes act in series to accurately replicate the eukaryotic nuclear genome. The
major replicative DNA polymerases strongly prevent mismatch formation, occasional …

Multiple RNA polymerase conformations and GreA: control of the fidelity of transcription

DA Erie, O Hajiseyedjavadi, MC Young, PH von Hippel - Science, 1993 - science.org
Pre-steady state kinetics of misincorporation were used to investigate the addition of single
nucleotides to nascent RNA by Escherichia coli RNA polymerase during transcription …

Interpreting the effects of small uncharged solutes on protein-folding equilibria

PR Davis-Searles, AJ Saunders, DA Erie… - Annual review of …, 2001 - annualreviews.org
▪ Abstract Proteins are designed to function in environments crowded by cosolutes, but most
studies of protein equilibria are conducted in dilute solution. While there is no doubt that …

DNA bending and unbending by MutS govern mismatch recognition and specificity

…, E Alani, P Hsieh, DA Erie - Proceedings of the …, 2003 - National Acad Sciences
DNA mismatch repair is central to the maintenance of genomic stability. It is initiated by the
recognition of base–base mismatches and insertion/deletion loops by the family of MutS …

Controlled manipulation of molecular samples with the nanomanipulator

…, S Paulson, S Washburn, DA Erie… - IEEE/ASME …, 2000 - ieeexplore.ieee.org
The nanoManipulator system adds a virtual-reality interface to an atomic-force microscope (AFM),
thus providing a tool that can be used by scientists to image and manipulate …

Osmolyte‐induced changes in protein conformational equilibria

…, DL Allen, GJ Pielak, DA Erie - Biopolymers …, 2000 - Wiley Online Library
Examining solute‐induced changes in protein conformational equilibria is a long‐standing
method for probing the role of water in maintaining protein stability. Interpreting the molecular …

Photothermal modulation for oscillating mode atomic force microscopy in solution

GC Ratcliff, DA Erie, R Superfine - Applied physics letters, 1998 - pubs.aip.org
Solution imaging using resonant techniques for atomic force microscopy is greatly simplified
by driving the cantilever directly. We have taken advantage of the temperature-sensitive …

Atomic force microscopy studies of DNA-wrapped carbon nanotube structure and binding to quantum dots

…, I Tessmer, HH Thorp, DA Erie - Journal of the American …, 2008 - ACS Publications
Single-stranded DNA is an effective noncovalent dispersant for individual single-walled
carbon nanotubes (CNTs) in aqueous solution, forming a CNT−DNA hybrid material that has …

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

…, L Kaustov, PJ Brown, CH Arrowsmith, DA Erie… - Elife, 2016 - elifesciences.org
10.7554/eLife.17101.001 The epigenetic inheritance of DNA methylation requires UHRF1,
a histone- and DNA-binding RING E3 ubiquitin ligase that recruits DNMT1 to sites of newly …