User profiles for Doudou Yu
Doudou YuGraduate Student, Brown University Verified email at brown.edu Cited by 605 |
Reprogramming to recover youthful epigenetic information and restore vision
Ageing is a degenerative process that leads to tissue dysfunction and death. A proposed cause
of ageing is the accumulation of epigenetic noise that disrupts gene expression patterns, …
of ageing is the accumulation of epigenetic noise that disrupts gene expression patterns, …
Reversal of ageing-and injury-induced vision loss by Tet-dependent epigenetic reprogramming
Ageing is a degenerative process leading to tissue dysfunction and death. A proposed cause
of ageing is the accumulation of epigenetic noise, which disrupts youthful gene expression …
of ageing is the accumulation of epigenetic noise, which disrupts youthful gene expression …
[HTML][HTML] Single-cell analysis of the aging female mouse hypothalamus
KH Hajdarovic, D Yu, LA Hassell, SA Evans, S Packer… - Nature aging, 2022 - nature.com
Alterations in metabolism, sleep patterns, body composition and hormone status are all key
features of aging. While the hypothalamus is a well-conserved brain region that controls …
features of aging. While the hypothalamus is a well-conserved brain region that controls …
[HTML][HTML] Understanding the aging hypothalamus, one cell at a time
The hypothalamus is a brain region that integrates signals from the periphery and the
environment to maintain organismal homeostasis. To do so, specialized hypothalamic …
environment to maintain organismal homeostasis. To do so, specialized hypothalamic …
[PDF][PDF] CellBiAge: Improved single-cell age classification using data binarization
D Yu, M Li, G Linghu, Y Hu, KH Hajdarovic, A Wang… - Cell reports, 2023 - cell.com
Aging is a major risk factor for many diseases. Accurate methods for predicting age in
specific cell types are essential to understand the heterogeneity of aging and to assess …
specific cell types are essential to understand the heterogeneity of aging and to assess …
[HTML][HTML] Incidence and influencing factors of fertility concerns in breast cancer in young women: a systematic review and meta-analysis
…, H Jiang, H Lin, J He, S Fan, L Yang, D Yu… - Frontiers in …, 2023 - frontiersin.org
Objective This systematic review and meta-analysis aimed to evaluate the prevalence and
influencing factors of fertility concerns in breast cancer in young women. Methods A literature …
influencing factors of fertility concerns in breast cancer in young women. Methods A literature …
[HTML][HTML] Reversal of aging-induced and glaucoma-induced vision loss by in vivo epigenetic reprogramming
Purpose: DNA methylation (Horvath epigenetic clock) is a biomarker of aging, but whether
accumulating epigenetic signals simply denote age or regulate aging is unclear. In vitro …
accumulating epigenetic signals simply denote age or regulate aging is unclear. In vitro …
[HTML][HTML] Fertility concerns in cancer patients: a bibliometric analysis via CiteSpace: A review
J Shen, H Jiang, H Lin, S Fan, D Yu, L Yang, L Chen - Medicine, 2023 - journals.lww.com
Fertility concerns are a pervasive issue but very subtle in patients with cancer. Though various
studies have focused on fertility concerns, limited research endeavor has been dedicated …
studies have focused on fertility concerns, limited research endeavor has been dedicated …
[HTML][HTML] The effect of micronutrient on thyroid cancer risk: a Mendelian randomization study
…, H Zhang, H Jiang, H Lin, J He, S Fan, D Yu… - Frontiers in …, 2024 - frontiersin.org
Background The effect of micronutrients on thyroid cancer has been studied in observational
studies, however, the cause of relationships has not yet been determined. Thyroid cancer …
studies, however, the cause of relationships has not yet been determined. Thyroid cancer …
Association between educational attainment and thyroid cancer: evidence from a univariable and multivariable Mendelian randomization study
S Fan, H Jiang, J Shen, H Lin, D Yu, L Yang, N Zheng… - Endocrine, 2024 - Springer
Background Thyroid cancer and educational attainment have been related in observational
studies. It is unclear if these correlations indicate causative relationships. Methods Using …
studies. It is unclear if these correlations indicate causative relationships. Methods Using …