The rich fossil record of equids has made them a model for evolutionary processes 1 . Here
we present a 1.12-times coverage draft genome from a horse bone recovered from …

The role of histone modifications in transcription remains incompletely understood. Here,
we examine the relationship between histone modifications and transcription using …

Horses, asses, and zebras belong to a single genus, Equus, which emerged 4.0–4.5 Mya.
Although the equine fossil record represents a textbook example of evolution, the succession …

Recent advances in genomic sequencing technology and computational assembly methods
have allowed scientists to improve reference genome assemblies in terms of contiguity and …

Background Autologous and allogeneic adult mesenchymal stem/stromal cells (MSCs) are
increasingly being investigated for treating a wide range of clinical diseases. Allogeneic …

Introduction The horse is a valuable species to assess the effect of allogeneic mesenchymal
stromal cells (MSCs) in regenerative treatments. No studies to date have examined …

The discovery of genomic imprinting through studies of manipulated mouse embryos indicated
that the paternal genome has a major influence on placental development. However, …

In horses prone to developing recurrent airway obstruction (RAO), we tested the hypotheses
that the cytokine profile in the bronchoalveolar lavage (BAL) cells of affected horses would …

Lavender Foal Syndrome (LFS) is a lethal inherited disease of horses with a suspected
autosomal recessive mode of inheritance. LFS has been primarily diagnosed in a subgroup of …

Introduction This study tested the hypothesis that Major Histocompatibility Complex (MHC)
incompatible equine mesenchymal stromal cells (MSCs) would induce cytotoxic antibodies to …