User profiles for Douglas G. Scofield

Douglas G. Scofield

Research Bioinformatician, Uppsala University
Verified email at ebc.uu.se
Cited by 3537

[HTML][HTML] The Norway spruce genome sequence and conifer genome evolution

…, A Wetterbom, A Zuccolo, YC Lin, DG Scofield… - Nature, 2013 - nature.com
Conifers have dominated forests for more than 200 million years and are of huge ecological
and economic importance. Here we present the draft assembly of the 20-gigabase genome …

Intron size, abundance, and distribution within untranslated regions of genes

X Hong, DG Scofield, M Lynch - Molecular biology and evolution, 2006 - academic.oup.com
Most research concerning the evolution of introns has largely considered introns within
coding sequences (CDSs), without regard for introns located within untranslated regions (UTRs) …

Khoe-San Genomes Reveal Unique Variation and Confirm the Deepest Population Divergence in Homo sapiens

…, LM Gattepaille, M Vicente, DG Scofield… - Molecular biology …, 2020 - academic.oup.com
The southern African indigenous Khoe-San populations harbor the most divergent lineages
of all living peoples. Exploring their genomes is key to understanding deep human history. …

[HTML][HTML] A major locus controls local adaptation and adaptive life history variation in a perennial plant

…, IH Michelson, A Johansson, B Nystedt, DG Scofield… - Genome biology, 2018 - Springer
Background The initiation of growth cessation and dormancy represent critical life-history
trade-offs between survival and growth and have important fitness effects in perennial plants. …

Mitosis, stature and evolution of plant mating systems: low-Φ and high-Φ plants

DG Scofield, ST Schultz - Proceedings of the Royal …, 2006 - royalsocietypublishing.org
There is a long-recognized association in plants between small stature and selfing, and
large stature and outcrossing. Inbreeding depression is central to several hypotheses for this …

Variation in linked selection and recombination drive genomic divergence during allopatric speciation of European and American aspens

J Wang, NR Street, DG Scofield… - Molecular Biology and …, 2016 - academic.oup.com
Despite the global economic and ecological importance of forest trees, the genomic basis of
differential adaptation and speciation in tree species is still poorly understood. Populus …

Natural Selection and Recombination Rate Variation Shape Nucleotide Polymorphism Across the Genomes of Three Related Populus Species

J Wang, NR Street, DG Scofield, PK Ingvarsson - Genetics, 2016 - academic.oup.com
A central aim of evolutionary genomics is to identify the relative roles that various evolutionary
forces have played in generating and shaping genetic variation within and among species…

Functional and evolutionary genomic inferences in Populus through genome and population sequencing of American and European aspen

…, MP Hoeppner, H Lantz, DG Scofield… - Proceedings of the …, 2018 - National Acad Sciences
The Populus genus is one of the major plant model systems, but genomic resources have
thus far primarily been available for poplar species, and primarily Populus trichocarpa (Torr. & …

Haploid selection within a single ejaculate increases offspring fitness

…, K Nakhro, S Rudolf, DG Scofield… - Proceedings of the …, 2017 - National Acad Sciences
An inescapable consequence of sex in eukaryotes is the evolution of a biphasic life cycle
with alternating diploid and haploid phases. The occurrence of selection during the haploid …

[HTML][HTML] Bacteria colonising Penstemon digitalis show volatile and tissue-specific responses to a natural concentration range of the floral volatile linalool

RCF Burdon, RR Junker, DG Scofield… - Chemoecology, 2018 - Springer
Bacteria on floral tissue can have negative effects by consuming resources and affecting
nectar quality, which subsequently could reduce pollinator visitation and plant fitness. Plants …