Objective We compared the effects of high-intensity interval training (HIIT) and moderate-intensity
continuous training (MICT) on insulin sensitivity and other important metabolic …

How regular physical activity is able to improve health remains poorly understood. The
release of factors from skeletal muscle following exercise has been proposed as a possible …

Alterations in the inflammatory state, metabolic function, and structure of subcutaneous
adipose tissue (SAT) can impact the development of insulin resistance in obesity. Exercise can …

The “canonical” function of Pax7+ muscle stem cells (satellite cells) during hypertrophic
growth of adult muscle fibers is myonuclear donation via fusion to support increased …

Using in vivo muscle stem cell (satellite cell)-specific extracellular vesicle (EV) tracking,
satellite cell depletion, in vitro cell culture, and single-cell RNA sequencing, we show satellite …

Excessive adipose tissue mass underlies much of the metabolic health complications in
obesity. Although exercise training is known to improve metabolic health in individuals with …

Background Skeletal muscle (SkM) is a large, secretory organ that produces and releases
myokines that can have autocrine, paracrine, and endocrine effects. Whether extracellular …

Background Translational capacity (ie ribosomal mass) is a key determinant of protein
synthesis and has been associated with skeletal muscle hypertrophy. The role of translational …

Aim Interventions that decrease atrophy during disuse are desperately needed to maintain
muscle mass. We recently found that massage as a mechanotherapy can improve muscle …

Objective The aims of this study were: 1) to assess relationships among insulin‐mediated
glucose uptake with standard clinical outcomes and deep‐phenotyping measures (including …